Imperial College London
Portrait Picture

Dr James A Bull

Faculty of Natural Sciences, Department of Chemistry

Reader in Synthetic Chemistry
 
 
 
//

Contact

 

+44 (0)20 7594 5811j.bull Website

 
 
//

Location

 

501bMolecular Sciences Research HubWhite City Campus

//

Summary

 

Publications

Citation

BibTex format

@article{Boultwood:2019:10.1021/acsomega.8b03019,
author = {Boultwood, T and Bull, J},
doi = {10.1021/acsomega.8b03019},
journal = {ACS Omega},
pages = {870--879},
title = {Synthesis of selenoaziridines: a study on stereochemical outcomes of the reaction of aziridine radicals and anions generated from iodoaziridines},
url = {http://dx.doi.org/10.1021/acsomega.8b03019},
volume = {4},
year = {2019}
}
Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - The synthesis of a new functional group in the form of selenyl-substituted aziridines is described. Selenoaziridines are stereoselectively prepared by functionalization of intact aziridine precursors involving radical and anionic intermediates. Radicals are generated from cis-N-Ts iodoaziridines by activation of the C–I bond using alkoxides as a source of single electrons. These form predominantly trans-substituted seleno-aziridines dependent on the size of the diselenide. cis-Aziridinyllithiums generated by Li–I exchange also react with diselenides stereospecifically to form a range of cis-selenoaziridines. Proposals for the stereochemical outcome are presented.
AU  - Boultwood,T
AU  - Bull,J
DO  - 10.1021/acsomega.8b03019
EP  - 879
PY  - 2019///
SN  - 2470-1343
SP  - 870
TI  - Synthesis of selenoaziridines: a study on stereochemical outcomes of the reaction of aziridine radicals and anions generated from iodoaziridines
T2  - ACS Omega
UR  - http://dx.doi.org/10.1021/acsomega.8b03019
UR  - https://pubs.acs.org/doi/10.1021/acsomega.8b03019
UR  - http://hdl.handle.net/10044/1/66912
VL  - 4
ER  -
Download