Imperial College London
Alternate

ProfessorJaneDavies

Faculty of Medicine, National Heart & Lung Institute

Professor of Paediatric Respirology & Experimental Medicine
 
 
 
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Contact

 

+44 (0)20 7594 7973j.c.davies

 
 
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Assistant

 

Mrs Gina Rivellini +44 (0)20 7594 7986

 
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Location

 

G44Emmanuel Kaye BuildingRoyal Brompton Campus

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Summary

 

Publications

Publication Type
Year
to

452 results found

Davies JC, Alton EW, 2009, Monitoring respiratory disease severity in cystic fibrosis., Respir Care, Vol: 54, Pages: 606-617, ISSN: 0020-1324

Measurements of disease severity provide a guide for the physician to tailor therapies, for the patient and family to gauge progress, and are required for clinical trials. For many respiratory diseases, including cystic fibrosis, sensitive, noninvasive measurements are few, and some of those that are available are applicable only to certain subgroups of patients or lack sufficient sensitivity. We discuss currently available measurements in 4 groups: physiology, infection, inflammation, and radiology. For each group we highlight strengths and weaknesses, ask how we could improve upon these, and provide details of alternative methods.

Journal article

Davies JC, Alton EWFW, 2009, Monitoring Respiratory Disease Severity in Cystic Fibrosis, 43rd Respiratory Care Journal Conference on Respiratory Care and Cystic Fibrosis, Publisher: DAEDALUS ENTERPRISES INC, Pages: 606-615, ISSN: 0020-1324

Conference paper

Pringle IA, Hewitt A-M, Connolly M, Lawton AE, Voase NWG, Larsen M, Manvelle M, Donovan J, Mohamedhossen MH, Davies J, Alton EWFW, McLachlan G, Collie DD, Hyde SC, Gill DRet al., 2009, Exploiting Single-Cell-PCR Technology To Determine the Percentage of Transfected Cells in the Respiratory Epithelium, 12th Annual Meeting of the American Society of Gene Therapy, Publisher: NATURE PUBLISHING GROUP, Pages: S125-S125, ISSN: 1525-0016

Conference paper

Fidler KJ, Hilliard TN, Bush A, Johnson M, Geddes DM, Turner MW, Alton EWFW, Klein NJ, Davies JCet al., 2009, Mannose-binding lectin is present in the infected airway: a possible pulmonary defence mechanism, THORAX, Vol: 64, Pages: 150-155, ISSN: 0040-6376

Journal article

Regamey N, Balfour-Lynn I, Rosenthal M, Hogg C, Bush A, Davies JCet al., 2009, Time Required to Obtain Endobronchial Biopsies in Children During Fiberoptic Bronchoscopy, PEDIATRIC PULMONOLOGY, Vol: 44, Pages: 76-79, ISSN: 8755-6863

Journal article

Macleod KA, Horsley AR, Bell NJ, Reid P, Davies J, Alton EW, Greening AP, Innes JA, Cunningham Set al., 2009, Lung Clearance Index, in Children and Adults with Cystic Fibrosis, Is More Sensitive to Progressive Airways Disease Than Standard Spirometry., AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 179, ISSN: 1073-449X

Journal article

Davies JC, Gill D, Griesenbach U, Voase N, Davies G, Higgins T, Innes JA, Boyd C, Porteous D, Hyde S, Alton EWet al., 2009, EVALUATION OF SAFETY AND GENE EXPRESSION WITH A SINGLE DOSE OF PGM169/GL67A ADMINISTERED TO THE NOSE AND LUNG OF INDIVIDUALS WITH CF: THE UK CF GENE THERAPY CONSORTIUM "PILOT STUDY", PEDIATRIC PULMONOLOGY, Pages: 305-306, ISSN: 8755-6863

Journal article

Tan H, Regamey N, Hilliard T, Alton E, Bush A, Lloyd CM, Davies Jet al., 2009, EXPLORING THE PHENOTYPE OF THE LYMPHOCYTIC INFILTRATE IN THE CF AIRWAY: DO IL17+CELLS PLAY A ROLE IN DISEASE PATHOGENESIS?, PEDIATRIC PULMONOLOGY, Pages: 254-254, ISSN: 8755-6863

Journal article

Davies JC, MacLean F, Nilsson E, Kollberg H, Alton EWet al., 2009, INCREASED ADHERENCE OF <i>P</i>. <i>AERUGINOSA</i> TO BUCCAL EPITHELIAL CELLS IN THE PRESENCE OF SPECIFIC ANTI-PSEUDOMONAS IGY, PEDIATRIC PULMONOLOGY, Pages: 337-337, ISSN: 8755-6863

Journal article

Voase NW, Davies G, Reid PA, Macleod KA, Dewar MH, Bell NJ, Saunders C, Greening AP, Cunningham S, Innes JA, Alton EW, Davies JCet al., 2009, SUCCESS AND UTILITY OF SPUTUM INDUCTION IN NON-EXPECTORATING CF SUBJECTS: DATA FROM THE UK CF GENE THERAPY RUN-IN STUDY, PEDIATRIC PULMONOLOGY, Pages: 337-338, ISSN: 8755-6863

Journal article

Sumner-Jones S, McCormick D, Coles R, Pringle IA, McLachlan G, Collie DD, Vrettou C, Davies JC, Alton EW, Gill DR, Hyde SCet al., 2009, OPTIMISATION OF MOLECULAR ASSAYS FOR CLINICAL TRIAL OF GL67A/PDNA DELIVERY TO NOSE AND LUNG OF CF PATIENTS, PEDIATRIC PULMONOLOGY, Pages: 306-306, ISSN: 8755-6863

Journal article

Donovan J, Davies JC, Alton EW, 2009, OPTIMISING SPUTUM PROCESSING FOR ANALYSIS OF INFLAMMATORY MARKERS IN CF: REMOVAL OF DITHIOTHREITOL BY DIALYSIS DOES NOT IMPROVE DETECTION OF CYTOKINES, PEDIATRIC PULMONOLOGY, Pages: 357-357, ISSN: 8755-6863

Journal article

Ryall B, Davies JC, Wilson R, Shoemark A, Williams HDet al., 2008, <i>Pseudomonas aeruginosa</i>, cyanide accumulation and lung function in CF and non-CF bronchiectasis patients, EUROPEAN RESPIRATORY JOURNAL, Vol: 32, Pages: 740-747, ISSN: 0903-1936

Journal article

MacGregor G, Gray RD, Hilliard TN, Imrie M, Boyd AC, Alton EWFW, Bush A, Davies JC, Innes JA, Porteous DJ, Greening APet al., 2008, Biomarkers for cystic fibrosis lung disease: Application of SELDI-TOF mass spectrometry to BAL fluid, JOURNAL OF CYSTIC FIBROSIS, Vol: 7, Pages: 352-358, ISSN: 1569-1993

Journal article

Kozlowska WJ, Bush A, Wade A, Aurora P, Carr SB, Castle RA, Hoo A-F, Lum S, Price J, Ranganathan S, Saunders C, Stanojevic S, Stroobant J, Wallis C, Stocks Jet al., 2008, Lung function from infancy to the preschool years after clinical diagnosis of cystic fibrosis, AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 178, Pages: 42-49, ISSN: 1073-449X

Journal article

Hilliard TN, Zhu J, Farley R, Escudero-Garcia S, Wainwright BJ, Jeffery PK, Griesenbach U, Bush A, Davies JC, Alton EWFWet al., 2008, Nasal abnormalities in cystic fibrosis mice independent of infection and inflammation, AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, Vol: 39, Pages: 19-25, ISSN: 1044-1549

Journal article

Hyde SC, Pringle IA, Abdullah S, Lawton AE, Davies LA, Varathalingam A, Nunez-Alonso G, Green A-M, Bazzani RP, Sumner-Jones SG, Chan M, Li H, Yew NS, Cheng SH, Boyd AC, Davies JC, Griesenbach U, Porteous DJ, Sheppard DN, Munkonge FM, Alton EWFW, Gill DRet al., 2008, CpG-free plasmids confer reduced inflammation and sustained pulmonary gene expression, NATURE BIOTECHNOLOGY, Vol: 26, Pages: 549-551, ISSN: 1087-0156

Journal article

Regamey N, Ochs M, Hilliard TN, Muehlfeld C, Cornish N, Fleming L, Saglani S, Alton EWFW, Bush A, Jeffery PK, Davies JCet al., 2008, Increased airway smooth muscle mass in children with asthma, cystic fibrosis, and non-cystic fibrosis bronchiectasis, AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 177, Pages: 837-843, ISSN: 1073-449X

Journal article

Davidson H, Wilson A, Gray RD, Horsley A, Pringle I, McLachlan G, Gibson J, Holder E, Jones L, Doherty A, Coles R, Sumner-Jones S, Wasowicz M, Manvell M, Griesenbach U, Hyde SC, Gill DR, Davies J, Collie DDS, Alton E, Porteous DJ, Boyd ACet al., 2008, Development of an immunocytochemical assay to detect human CFTR expression following gene therapy, 5th Annual Conference of the British-Society-for-Gene-Therapy, Publisher: MARY ANN LIEBERT INC, Pages: 416-416, ISSN: 1043-0342

Conference paper

Davies JC, Cunningham S, Alton EWFW, Innes JAet al., 2008, Lung clearance index in CF: a sensitive marker of lung disease severity, THORAX, Vol: 63, Pages: 96-97, ISSN: 0040-6376

Journal article

Horsley AR, Gustafsson PM, Macleod KA, Saunders C, Greening AP, Porteous DJ, Davies JC, Cunningham S, Alton EWFW, Innes JAet al., 2008, Lung clearance index is a sensitive, repeatable and practical measure of airways disease in adults with cystic fibrosis, THORAX, Vol: 63, Pages: 135-140, ISSN: 0040-6376

Journal article

Regamey N, Hilliard TN, Saglani S, Zhu J, Balfour-Lynn IM, Rosenthal M, Jeftery PK, Alton EWFV, Bush A, Davies JCet al., 2008, Endobronchial biopsy in childhood, CHEST, Vol: 133, Pages: 312-312, ISSN: 0012-3692

Journal article

Davies JC, Alton EWFW, Bush A, 2007, Cystic fibrosis, BMJ-BRITISH MEDICAL JOURNAL, Vol: 335, Pages: 1255-1259, ISSN: 1756-1833

Journal article

Horsley AR, Aziz Z, Macleod KA, Saunders CJ, Meister M, Tyler P, Dewar M, Gray R, Voase N, Cunningham S, Greening AP, Davies JC, Alton EWFW, Hansell D, Innes JAet al., 2007, Functional and structural changes in the cystic fibrosis lung following antibiotic treatment for exacerbation, Winter Meeting of the British-Thoracic-Society, Publisher: B M J PUBLISHING GROUP, Pages: A31-A31, ISSN: 0040-6376

Conference paper

Hilliard TN, Regamey N, Shute JK, Nicholson AG, Alton EWFW, Bush A, Davies JCet al., 2007, Airway remodelling in children with cystic fibrosis, THORAX, Vol: 62, Pages: 1074-1080, ISSN: 0040-6376

Journal article

Griesenbach U, Jeswiet SB, Larsen MDB, Bakar Y, Voase NWG, Gammie FM, Mullard KE, Geddes DM, Davies JC, Alton EWFW, Marriott C, Gray R, Horsley A, Imrie M, Dewar M, Greening AP, Innes Aet al., 2007, UK cf gene therapy consortium tracking study: Change in sputum properties in response to IV antibiotics, Winter Meeting of the British-Thoracic-Society, Publisher: B M J PUBLISHING GROUP, Pages: A30-A30, ISSN: 0040-6376

Conference paper

Davies JC, Voase N, Dewar M, Mullard K, Gammie F, Saunders C, Horsley A, Gray R, Macleod K, Somerton L, Higgins T, Donovan J, Cornish N, Ashby D, Geddes D, Greening A, Cunningham S, Innes A, Alton Eet al., 2007, Uk CF gene therapy consortium tracking study: Response of clinically available assays to intravenous antibiotics, Winter Meeting of the British-Thoracic-Society, Publisher: B M J PUBLISHING GROUP, Pages: A30-A30, ISSN: 0040-6376

Conference paper

Aziz ZA, Wells A, Meister M, Tyler P, Davies J, Alton E, Innes A, Gray R, Horsley A, Hansell Det al., 2007, Computed tomography in infective exacerbations in cystic fibrosis: Serial change and observer agreement, Winter Meeting of the British-Thoracic-Society, Publisher: B M J PUBLISHING GROUP, Pages: A30-A31, ISSN: 0040-6376

Conference paper

Hilliard TN, Sukhani S, Francis J, Madden N, Rosenthal M, Balfour-Lynn I, Bush A, Davies JCet al., 2007, Bronchoscopy following diagnosis with cystic fibrosis, ARCHIVES OF DISEASE IN CHILDHOOD, Vol: 92, Pages: 898-899, ISSN: 0003-9888

Journal article

Bush A, Davies J, 2007, Non! to non-steroidal anti-inflammatory therapy for inflammatory lung disease in cystic fibrosis (at least at the moment), JOURNAL OF PEDIATRICS, Vol: 151, Pages: 228-230, ISSN: 0022-3476

Journal article

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