Imperial College London

DrJosephChallenger

Faculty of MedicineSchool of Public Health

Research Associate
 
 
 
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Contact

 

j.challenger Website

 
 
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Location

 

Norfolk PlaceSt Mary's Campus

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Summary

 

Summary

I am a post-doctoral research associate working in the malaria group with Tom Churcher in the Department of Infectious Disease Epidemiology. My current work includes modelling the potential impact of transmission-blocking vaccines and using experimental hut trials to evaluate novel insecticides.

I have also worked with Lucy Okell within the department, developing within-host models of both treated and untreated malaria infections.This modelling work enables us to estimate the impact that imperfect adherence to treatment has on patient outcomes.

My PhD was completed at The University of Manchester with Professor Alan McKane. My PhD work focused on stochastic population dynamics, with an emphasis on individual-based modelling. Following my PhD I spent two years at The University of Florence, working with Professor Duccio Fanelli.

Publications

Journals

de Jong RM, Meerstein-Kessel L, Da DF, et al., 2021, Monoclonal antibodies block transmission of genetically diverse Plasmodium falciparum strains to mosquitoes, Npj Vaccines, Vol:6, ISSN:2059-0105, Pages:1-9

Challenger JD, Foo CY, Wu Y, et al., 2021, Modelling upper respiratory viral load dynamics of SARS-CoV-2

Challenger J, Olivera Mesa D, Da DF, et al., 2021, Predicting the public health impact of a malaria transmission-blocking vaccine, Nature Communications, Vol:12, ISSN:2041-1723, Pages:1-12

Mumtaz R, Okell LC, Challenger J, 2020, Asymptomatic recrudescence after artemether-lumefantrine treatment for uncomplicated falciparum malaria: a systematic review and meta-analysis, Malaria Journal, Vol:19, ISSN:1475-2875

Mousa A, Al-Taiar A, Anstey NM, et al., 2020, The impact of delayed treatment of uncomplicated P. falciparum malaria on progression to severe malaria: a systematic review and a pooled multicentre individual-patient meta-analysis, Plos Medicine, Vol:17, ISSN:1549-1277, Pages:1-28

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