Imperial College London

DrJosephChallenger

Faculty of MedicineSchool of Public Health

Research Fellow
 
 
 
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Contact

 

j.challenger Website

 
 
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Location

 

Norfolk PlaceSt Mary's Campus

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Summary

 

Summary

I am a Research Fellow working in the malaria group with Tom Churcher in the Department of Infectious Disease Epidemiology. My current work includes modelling the potential impact of transmission-blocking vaccines and using experimental hut trials to evaluate novel insecticides.

I have also worked with Lucy Okell within the department, developing within-host models of both treated and untreated malaria infections.This modelling work enables us to estimate the impact that imperfect adherence to treatment has on patient outcomes.

My PhD was completed at The University of Manchester with Professor Alan McKane. My PhD work focused on stochastic population dynamics, with an emphasis on individual-based modelling. Following my PhD I spent two years at The University of Florence, working with Professor Duccio Fanelli.

Publications

Journals

Moradi Marjaneh M, Challenger J, salas A, et al., 2023, Analysis of blood and nasal epithelial transcriptomes to identify mechanisms associated with control of SARS-CoV-2 viral load in the upper respiratory tract, Journal of Infection, Vol:87, ISSN:0163-4453, Pages:538-550

Huang W, Rodrigues J, Bilgo E, et al., 2023, Delftia tsuruhatensis TC1 symbiont suppresses malaria transmission by anopheline mosquitoes, Science, Vol:381, ISSN:1095-9203, Pages:533-540

Challenger JD, van Beek SW, Heine RT, et al., 2023, Modelling the impact of a highly potent Plasmodium falciparum transmission-blocking monoclonal antibody in areas of seasonal malaria transmission, Journal of Infectious Diseases, Vol:228, ISSN:0022-1899, Pages:212-223

Challenger J, Nash RK, Ngufor C, et al., 2023, Assessing the variability in experimental hut trials evaluating insecticide-treated nets against malaria vectors, Current Research in Parasitology & Vector-borne Diseases, Vol:3, ISSN:2667-114X, Pages:1-11

Okell LC, Kwambai TK, Dhabangi A, et al., 2023, Projected health impact of post-discharge malaria chemoprevention among children with severe malarial anaemia in Africa, Nature Communications, Vol:14, ISSN:2041-1723, Pages:1-10

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