Imperial College London

Dr Jonathan M Clarke

Faculty of Natural SciencesDepartment of Mathematics

Sir Henry Wellcome Postdoctoral Fellow



j.clarke Website




St Marys Multiple BuildingsSt Mary's Campus





Jonathan is a Sir Henry Wellcome Postdoctoral Fellow in the EPSRC Centre for Mathematics of Precision Healthcare at Imperial College London.

Jonathan aims to explore three pressing questions facing health systems across the world: How should clinical information be shared across the healthcare system? How will changes to clinical services affect patients and clinicians? How can we organise primary and secondary care services to make patient care safer, fairer, and more efficient?

He applies the latest methodological techniques in data science and network analysis to explore healthcare in the National Health Service and internationally as a complex system, and in doing so empower patients, clinicians and policy makers to make informed decisions to improve how healthcare is delivered.

Jonathan graduated from the University of Cambridge where he studied Anthropology and Clinical Medicine as a Windsor Bachelor Scholar at Emmanuel College. He began his clinical career as an Academic Foundation Programme doctor in London, before being appointed as an Academic Clinical Fellow in General Surgery at the Institute of Global Health Innovation at Imperial College London.

A general surgeon by training, Jonathan is a Member of the Royal College of Surgeons and holds a Masters in Public Health from Harvard University where he was a Kennedy Scholar. More recently he returned to Harvard University as a Visiting Fellow in Biostatistics with the Onnela Lab.

His doctoral thesis ‘The Power of Connections: Mapping the Behaviour of Healthcare Networks’, supervised by Professors Mauricio Barahona and Ara Darzi, applied network analysis and machine learning to understand health systems as networks produced by the everyday interactions between patients and care providers.

He is fascinated by the delivery of healthcare in its broader societal context. He focuses on how the vast array of available health and social information may be harnessed to address health inequality in the United Kingdom and internationally.

He has worked internationally with the United Nations, World Health Organization, Médecins du Monde and the Francois Xavier Bagnoud Centre for Health and Human Rights at Harvard University to document the human rights infringements across Europe that result from discriminatory health policies towards migrants. He currently serves as an advisor to the Institute for the Future of Work on the relationship between good work and good health. Jonathan is also a Scientific Advisor to the Helix Centre for Design in Healthcare where he examines how the generation, synthesis and utilisation of clinical guidance affects patient care.



Lugo-Palacios DG, Clarke JM, Kristensen SR, 2023, Back to basics: A mediation analysis approach to addressing the fundamental questions of integrated care evaluations., Health Econ, Vol:32, Pages:2080-2097

Gujjuri RR, Clarke JM, Elliott JA, et al., 2023, Predicting long-term survival and time-to-recurrence after esophagectomy in patients with esophageal cancer - Development and validation of a multivariate prediction model., Ann Surg, Vol:277, Pages:971-978

Beaney T, Clarke J, Alboksmaty A, et al., 2023, Evaluating the impact of a pulse oximetry remote monitoring programme on mortality and healthcare utilisation in patients with COVID-19 assessed in Emergency Departments in England: a retrospective matched cohort study, Emergency Medicine Journal, Vol:40, ISSN:1472-0205, Pages:460-465

Clarke J, Beaney T, Alboksmaty A, et al., 2023, Factors associated with enrolment into a national COVID-19 pulse oximetry remote monitoring programme in England: a retrospective observational study, The Lancet: Digital Health, Vol:5, ISSN:2589-7500, Pages:e194-e205

Beaney T, Clarke J, 2022, Home oxygen monitoring and therapy: learning from the pandemic, Current Opinion in Critical Care

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