Imperial College London
Portrait Picture

Dr Jonathan M Clarke

Faculty of Natural Sciences, Department of Mathematics

Sir Henry Wellcome Postdoctoral Fellow
 
 
 
//

Contact

 

j.clarke Website

 
 
//

Location

 

St Marys Multiple BuildingsSt Mary's Campus

//

Summary

 

Publications

Citation

BibTex format

@article{Appelbaum:2020:10.1136/archdischild-2019-318370,
author = {Appelbaum, N and Rodriguez, Gonzalvez C and Clarke, J},
doi = {10.1136/archdischild-2019-318370},
journal = {Archives of Disease in Childhood},
pages = {516--517},
title = {Ideal bodyweight in the precision era: recommendations in obesity require thought for computer assisted prescribing},
url = {http://dx.doi.org/10.1136/archdischild-2019-318370},
volume = {105},
year = {2020}
}
Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - As the prevalence of childhood obesity continues to increase, there has been comparatively slow growth in the literature describing how best to dose obese children. For medications with low  lipid  solubility  where  doses  are  calculated  by  the  total  body  weight  (TBW)  of  the  child, increasing adiposity may lead to the administration of doses well in excess of that required for therapeutic effect, and potentially beyond the safe therapeutic interval of the medication. This concern underlies recommendations to use alternative bodyweight measurements for some medications when dosing obese children.
AU  - Appelbaum,N
AU  - Rodriguez,Gonzalvez C
AU  - Clarke,J
DO  - 10.1136/archdischild-2019-318370
EP  - 517
PY  - 2020///
SN  - 0003-9888
SP  - 516
TI  - Ideal bodyweight in the precision era: recommendations in obesity require thought for computer assisted prescribing
T2  - Archives of Disease in Childhood
UR  - http://dx.doi.org/10.1136/archdischild-2019-318370
UR  - http://hdl.handle.net/10044/1/75282
VL  - 105
ER  -
Download