Imperial College London

Dr Jonathan M Clarke

Faculty of Natural SciencesDepartment of Mathematics

Sir Henry Wellcome Postdoctoral Fellow
 
 
 
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Contact

 

j.clarke Website

 
 
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Location

 

St Marys Multiple BuildingsSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Beaney:2022:10.1038/s41467-022-29880-7,
author = {Beaney, T and Neves, AL and Alboksmaty, A and Ashrafian, H and Flott, K and Fowler, A and Benger, J and Aylin, P and Elkin, S and Darzi, A and Clarke, J},
doi = {10.1038/s41467-022-29880-7},
journal = {Nature Communications},
pages = {1--9},
title = {Trends and associated factors for Covid-19 hospitalisation and fatality risk in 2.3 million adults in England},
url = {http://dx.doi.org/10.1038/s41467-022-29880-7},
volume = {13},
year = {2022}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - The Covid-19 mortality rate varies between countries and over time but the extent to which this is explained by the underlying risk in those infected is unclear. Using data on all adults in England with a positive Covid-19 test between 1st October 2020 and 30th April 2021 linked to clinical records, we examined trends and risk factors for hospital admission and mortality. Of 2,311,282 people included in the study, 164,046 (7.1%) were admitted and 53,156 (2.3%) died within 28 days of a positive Covid-19 test. We found significant variation in the case hospitalisation and mortality risk over time, which remained after accounting for the underlying risk of those infected. Older age groups, males, those resident in areas of greater socioeconomic deprivation, and those with obesity had higher odds of admission and death. People with severe mental illness and learning disability had the highest odds of admission and death. Our findings highlight both the role of external factors in Covid-19 admission and mortality risk and the need for more proactive care in the most vulnerable groups.
AU - Beaney,T
AU - Neves,AL
AU - Alboksmaty,A
AU - Ashrafian,H
AU - Flott,K
AU - Fowler,A
AU - Benger,J
AU - Aylin,P
AU - Elkin,S
AU - Darzi,A
AU - Clarke,J
DO - 10.1038/s41467-022-29880-7
EP - 9
PY - 2022///
SN - 2041-1723
SP - 1
TI - Trends and associated factors for Covid-19 hospitalisation and fatality risk in 2.3 million adults in England
T2 - Nature Communications
UR - http://dx.doi.org/10.1038/s41467-022-29880-7
UR - https://www.nature.com/articles/s41467-022-29880-7
UR - http://hdl.handle.net/10044/1/96350
VL - 13
ER -