Imperial College London
Alternate

ProfessorJustinCobb

Faculty of Medicine, Department of Surgery & Cancer

Chair in Orthopaedic Surgery
 
 
 
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Contact

 

+44 (0)20 7594 5534j.cobb Website

 
 
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Assistant

 

Miss Colinette Hazel +44 (0)20 7594 2725

 
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Location

 

c/oSir Michael Uren HubWhite City Campus

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Summary

 

Publications

Citation

BibTex format

@article{Stoddart:2021:10.1016/j.joca.2020.10.011,
author = {Stoddart, J and Dandridge, O and Garner, A and Cobb, J and van, Arkel RJ},
doi = {10.1016/j.joca.2020.10.011},
journal = {Osteoarthritis and Cartilage},
pages = {445--455},
title = {The compartmental distribution of knee osteoarthritis – a systematic review and meta-analysis},
url = {http://dx.doi.org/10.1016/j.joca.2020.10.011},
volume = {29},
year = {2021}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - ObjectivesFor a population with knee osteoarthritis (OA), determine: 1) the prevalence of single compartmental, bicompartmental and tricompartmental OA, 2) the prevalence of isolated medial tibiofemoral, lateral tibiofemoral, or patellofemoral OA, and combinations thereof.MethodsPubMed and Web of Science databases, and reference lists of identified studies, were searched to find studies which reported on the compartmental distribution and prevalence of knee OA. Two independent reviewers assessed studies against pre-defined inclusion criteria and prevalence data were extracted along with subject characteristics. The methodological quality of each included study was assessed. A random-effects model meta-analysis was performed for each OA category to estimate the relative prevalence of OA in the knee compartments amongst people with knee OA.Results16 studies (3,786 knees) met the inclusion criteria. High heterogeneity was measured. Normalised for knees with OA, estimated prevalence rates (95% CI) were: single compartmental 50% (31.5–58.3%), bicompartmental 33% (23.1–37.2%) and tricompartmental only 17% (8.8–24.8%). Isolated medial tibiofemoral OA, isolated patellofemoral OA, and combined medial tibiofemoral and patellofemoral OA were more common than tricompartmental disease, occurring in 27% (15.2–31.1%), 18% (9.9–22.7%) and 23% (14.1–27.3%) of people respectively. Single/bicompartmental patterns of disease involving the lateral tibiofemoral compartment were less common, summing to 15% (8.5–18.7%).ConclusionThree-quarters of people with knee OA do not have tricompartmental disease. This is not reflected in the frequency with which partial and combined partial knee arthroplasties are currently used.Trial registration numberPROSPERO systematic review protocol (CRD42019140345).KeywordsGonarthrosisUnicompartmentalBicompartmentalPrevalenceEpidemiology
AU  - Stoddart,J
AU  - Dandridge,O
AU  - Garner,A
AU  - Cobb,J
AU  - van,Arkel RJ
DO  - 10.1016/j.joca.2020.10.011
EP  - 455
PY  - 2021///
SN  - 1063-4584
SP  - 445
TI  - The compartmental distribution of knee osteoarthritis – a systematic review and meta-analysis
T2  - Osteoarthritis and Cartilage
UR  - http://dx.doi.org/10.1016/j.joca.2020.10.011
UR  - https://www.sciencedirect.com/science/article/pii/S1063458420311973
UR  - http://hdl.handle.net/10044/1/84982
VL  - 29
ER  -
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