Imperial College London
Alternate

Mr Jeremy Crane MD FRCS

Faculty of Medicine, Department of Surgery & Cancer

Honorary Clinical Senior Lecturer
 
 
 
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Contact

 

+44 (0)20 3313 5346j.crane

 
 
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Assistant

 

Dr Adam McLean +44 (0)20 3313 5164

 
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Location

 

Hammersmith HouseHammersmith HospitalHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Oskrochi:2015:10.1016/j.ejvs.2015.08.016,
author = {Oskrochi, Y and Razi, K and Stebbing, J and Crane, J},
doi = {10.1016/j.ejvs.2015.08.016},
journal = {European Journal of Vascular and Endovascular Surgery},
pages = {127--133},
title = {Angiosarcoma and Dialysis-related Arteriovenous Fistulae: A Comprehensive Review.},
url = {http://dx.doi.org/10.1016/j.ejvs.2015.08.016},
volume = {51},
year = {2015}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - OBJECTIVE/BACKGROUND: To conduct a comprehensive review of cases, presentation, diagnosis, and management of angiosarcoma in arteriovenous fistulae (AVF) created for haemodialysis. METHODS: Two authors independently conducted systematic searches and extraction of articles from the Embase, AMED, Health Management Information Consortium, and MEDLINE databases in keeping with the inclusion/exclusion criteria and Preferred Reporting Items for Systematic Reviews and Meta-Analyses standards. RESULTS: Twenty-two unique patient cases were identified; 20 of the cases were men and mean ± SD age of presentation was 54.9 ± 13.6 years. Nineteen cases were post-transplant and 18 were on antirejection agents. The most common presenting symptom was pain, with or without a mass. The initial diagnosis was most often thrombosis/infection of the AVF and the diagnostic interval to a correct diagnosis of angiosarcoma was between 2 and 40 weeks. Mean ± SD time to presentation of symptoms from fistula formation was 118.9 ± 57.5 months, while from transplant it was 96.9 ± 70.0 months. Amputation was the most common treatment modality and mean ± SD survival was 8.8 ± 3.7 months. CONCLUSION: Angiosarcoma should be suspected in previously quiescent AVF that presents with pain. The presence of a rapidly enlarging mass or bleeding/bruising should be taken as alarm indicators and warrant urgent investigation in accordance with local cancer guidelines. Any surgical procedure should involve histological samples as a matter of course.
AU  - Oskrochi,Y
AU  - Razi,K
AU  - Stebbing,J
AU  - Crane,J
DO  - 10.1016/j.ejvs.2015.08.016
EP  - 133
PY  - 2015///
SN  - 1532-2165
SP  - 127
TI  - Angiosarcoma and Dialysis-related Arteriovenous Fistulae: A Comprehensive Review.
T2  - European Journal of Vascular and Endovascular Surgery
UR  - http://dx.doi.org/10.1016/j.ejvs.2015.08.016
VL  - 51
ER  -
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