Summary
Jorge is currently a Newton Fellow at the Imperial College London within the Department of Chemistry in the Supramolecular and Medicinal Inorganic Chemistry group (http://www3.imperial.ac.uk/medinchem). He is sponsored by the Royal Society and his research interest deals on (i) the design and synthesis of new molecular probes to (ii) evaluate the interaction with unusual DNA/RNA structures such as mismatches, triplexes or quadruplexes through in vitro and in vivo studies. The final aim is the identification of new selective drugs for unusual nucleic acid structures and their application in anticancer and diagnostic therapies.
Publications
Journals
Marin C, Inclán M, Ramirez-Macías MI, et al. , 2016, In vitro antileishmanial activity of aza-scorpiand macrocycles. Inhibition of the antioxidant enzyme iron superoxide dismutase, Rsc Advances, Vol:6, ISSN:2046-2069, Pages:17446-17455
González-García J, Tomić S, Lopera A, et al. , 2015, Aryl-bis-(scorpiand)-aza receptors differentiate between nucleotide monophosphates by a combination of aromatic, hydrogen bond and electrostatic interactions., Org Biomol Chem, Vol:13, Pages:1732-1740
Acosta-Rueda L, Delgado-Pinar E, Pitarch-Jarque J, et al. , 2015, Correlation between the molecular structure and the kinetics of decomposition of azamacrocyclic copper(<scp>ii</scp>) complexes, Dalton Transactions, Vol:44, ISSN:1477-9226, Pages:8255-8266
Dijanošić A, Miljanić S, Piantanida I, et al. , 2014, Revealing interactions between polyaza pyridinophane compounds and DNA/RNA polynucleotides by SERS spectroscopy, Journal of Raman Spectroscopy, Vol:45, ISSN:0377-0486, Pages:863-872
Begum RA, Day VW, Kumar M, et al. , 2014, M⋯H–C interaction – Agostic or not: A comparison of phenyl- versus pyridyl-bridged transition metal dimers, Inorganica Chimica Acta, Vol:417, ISSN:0020-1693, Pages:287-293