Imperial College London


Faculty of MedicineNational Heart & Lung Institute

Professor of Cellular Biophysics



+44 (0)20 7594 2736j.gorelik Website




Miss Cheryl Costello +44 (0)20 7594 3001




429ICTEM buildingHammersmith Campus





Julia Gorelik is Professor of Cellular Biophysics, within the Cardiovascular Science Division at the National Heart and Lung Institute, Imperial College London.

She is working in the interface between biophysics and cardiovascular Research. She obtained her Ph.D. in Cell Biology from St-Petersburg's Institute of Cytology, Russian Academy of Science in 1996. She spent 7 years working with Professor Yuri Korchev (Imperial College, Hammersmith Campus) who was the first to develop a new high resolution microscopic technique that is suitable for studying living cells - Scanning Ion Conductance Microscopy (SICM).

Dr Gorelik has a long-standing interest in the heart, which led her to develop the SICM to measure contraction, rhythm and calcium dynamics of cardiomyocytes simultaneously, allowing the study arrhythmias and heart failure conditions on cultured heart cells. She built a SICM microscope at Brompton Campus and combined it with fluorescence resonance energy transfer (FRET) technique for study spatial distribution of beta-adrenoreceptors on the surface of the cardiomyocytes. Dr Gorelik is a scientist with an extensive network of collaborators.

Finally, in 2010, Dr Gorelik was awarded an Imperial College Research Excellence Award to study 'New Nanoscale Technique to Study cAMP/cGMP Localisation in Cardiovascular Tissue'.



Wright P, Gorelik J, 2022, Junctophillin-2: Coupling Hopes for Cardiac Gene Therapy to Gene Transcription, Circulation Research, Vol:130, ISSN:0009-7330, Pages:1318-1320

Ramuz M, Diakonov I, Dunsby C, et al., 2022, MultiFRET: A Detailed Protocol for High-Throughput Multiplexed Ratiometric FRET., Methods Mol Biol, Vol:2483, Pages:33-59


Nunez-Toldra R, Kirwin T, Ferraro E, et al., 2022, Mechanosensitive molecular mechanisms of myocardial fibrosis in living myocardial slices, WILEY PERIODICALS, INC, Pages:1400-1412, ISSN:2055-5822

Francis AJ, Firth JM, Gorelik J, et al., 2021, Activation of GPER limits adverse changes to Ca2+signalling and arrhythmogenic activity in cardiomyocytes of ovariectomised guinea pigs, OXFORD UNIV PRESS, Pages:3208-3208, ISSN:0195-668X

Tikhomirov R, Reilly-O'donnell B, Lucarelli C, et al., 2021, Identification of miRNA-497 and miRNA-27b-5p as potential diagnostic markers of cardiac fibrosis, OXFORD UNIV PRESS, Pages:3344-3344, ISSN:0195-668X

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