Summary
I am a molecular microbiologist and earned my Ph.D. in 2006 working for the Spanish Research Council (CIB-CSIC) on environmental bacteria for the removal of pollutants. After that I moved into systems and synthetic biology of bacteria in postdoctoral stays at the National Center for Biotechnology (CSIC; Spain), the Center for Systems Biology at Harvard University (USA) and the Synthetic Biology Center at MIT (USA).
I was appointed as a Lecturer in Synthetic Biology in the University of Surrey in 2014 and promoted to Senior Lecturer in 2018. I joined the Dpt. of Life Sciences of Imperial College London in 2020. My research is currently sponsored by BBSRC, NERC, the Royal Society, the Leverhulme Foundation and the programme Horizon2020 of the European Union.
My research focuses on a number of topics at the interphase between synthetic biology and evolution. We are interested in understanding how evolution shapes the properties of proteins exhibiting quantum mechanisms in vivo, in the tradeoffs governing gene expression and in the dynamics of complex microbial communities. The applications of this research range from the development of novel methods to fight antibiotic resistant bacterial pathogens to the use of engineered microorganisms for the upcycling of plastic waste into molecules of added value.
For more information please visit my lab webpage.
Publications
Journals
Fernandez-Gonzalez A, Cowen S, Kim J, et al., 2022, Applicability of control materials to support gene promoter characterization and expression in engineered cells using digital PCR, Analytical Chemistry, Vol:94, ISSN:0003-2700, Pages:5566-5574
Hidalgo D, Martinez-Ortiz CA, Palsson BO, et al., 2022, Regulatory perturbations of ribosome allocation in bacteria reshape the growth proteome with a trade-off in adaptation capacity, Iscience, Vol:25, ISSN:2589-0042
Merali N, Chouari T, Kayani K, et al., 2022, A comprehensive review of the current and future role of the microbiome in pancreatic ductal adenocarcinoma, Cancers, Vol:14, ISSN:2072-6694, Pages:1-34
Narancic T, Salvador M, Hughes GM, et al., 2021, Genome analysis of the metabolically versatile Pseudomonas umsongensis GO16: the genetic basis for PET monomer upcycling into polyhydroxyalkanoates, Microbial Biotechnology, Vol:14, ISSN:1751-7907, Pages:2463-2480
Vieto S, Rojas-Gatjens D, Jimenez JI, et al., 2021, The potential of Pseudomonas for bioremediation of oxyanions, Environmental Microbiology Reports, Vol:13, ISSN:1758-2229, Pages:773-789