Publications
214 results found
Jain P, Chambers JC, Elliott P, et al., 2008, Coronary artery calcification as a predictor of increased coronary heart disease risk in UK Indian Asians, Annual Scientific Conference of the British-Cardiovascular-Society/British-Society-for-Cardiovascular-Research, Publisher: B M J PUBLISHING GROUP, Pages: A77-A77, ISSN: 1355-6037
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- Citations: 1
Chambers JC, Scott J, Meeran K, et al., 2008, Transcription factor 7-like 2, insulin action and risk of type 2 diabetes among Indian Asian and White European men, Annual Scientific Conference of the British-Cardiovascular-Society/British-Society-for-Cardiovascular-Research, Publisher: B M J PUBLISHING GROUP, Pages: A59-A59, ISSN: 1355-6037
Chambers JC, Zhang W, Zabaneh D, et al., 2008, Does genetic variation in FTO account for the increased risk of obesity and type 2 diabetes in UK Indian Asians?, Annual Scientific Conference of the British-Cardiovascular-Society/British-Society-for-Cardiovascular-Research, Publisher: B M J PUBLISHING GROUP, Pages: A58-A59, ISSN: 1355-6037
Chahal NS, Lim TK, Jain P, et al., 2008, Carotid intima-media thickness as a surrogate marker of atherosclerosis and cardiovascular disease risk in healthy UK Indian Asians and European whites, Annual Scientific Conference of the British-Cardiovascular-Society/British-Society-for-Cardiovascular-Research, Publisher: B M J PUBLISHING GROUP, Pages: A8-A9, ISSN: 1355-6037
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- Citations: 1
Chambers JC, Elliott P, Zabaneh D, et al., 2008, Common genetic variation near <i>MC4R</i> is associated with waist circumference and insulin resistance, NATURE GENETICS, Vol: 40, Pages: 716-718, ISSN: 1061-4036
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- Citations: 382
Williams ED, Steptoe A, Kooner JS, 2008, Psychosocial factors related to cardiovascular disease risk in UK South Asian men and women, ANNALS OF BEHAVIORAL MEDICINE, Vol: 35, Pages: S53-S53, ISSN: 0883-6612
Khurana R, Shalhoub J, Verma A, et al., 2008, Tubercular myocarditis presenting with ventricular tachycardia, NATURE CLINICAL PRACTICE CARDIOVASCULAR MEDICINE, Vol: 5, Pages: 169-174, ISSN: 1743-4297
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- Citations: 18
Williams ED, Kooner I, Steptoe A, et al., 2008, Psychosocial factors related to cardiovascular disease risk in UK South Asian men: A preliminary study (vol 12, pg 559, 2007), BRITISH JOURNAL OF HEALTH PSYCHOLOGY, Vol: 13, Pages: 188-188, ISSN: 1359-107X
Kooner JS, Chambers JC, Aguilar-Salinas CA, et al., 2008, Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides, Nature Genetics
Williams ED, Kooner I, Steptoe A, et al., 2007, Psychosocial factors related to cardiovascular disease risk in UK South Asian men: A preliminary study, BRITISH JOURNAL OF HEALTH PSYCHOLOGY, Vol: 12, Pages: 559-570, ISSN: 1359-107X
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- Citations: 16
Chambers JC, Scott J, Hinds DA, et al., 2007, A genome-wide scan identifies novel and known DNA variants associated with component phenotypes of metabolic syndrome, 80th Annual Scientific Session of the American-Heart-Association, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: 507-507, ISSN: 0009-7322
Zabaneh D, Chambers JC, Elliott P, et al., 2007, Estimating heritabilities and genetic correlations of insulin resistance and related metabolic traits in Indian families using a multivariate maximum likelihood approach, 16th Annual Meeting of the International-Genetic-Epidemiology-Society, Publisher: WILEY-LISS, Pages: 651-651, ISSN: 0741-0395
Chaturvedi N, Coady E, Mayet J, et al., 2007, Indian Asian men have less peripheral arterial disease than European men for equivalent levels of coronary disease, ATHEROSCLEROSIS, Vol: 193, Pages: 204-212, ISSN: 0021-9150
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- Citations: 39
Hughes AD, Coady E, Raynor S, et al., 2007, Reduced endothelial progenitor cells in European and South Asian men with atherosclerosis, EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, Vol: 37, Pages: 35-41, ISSN: 0014-2972
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- Citations: 23
Chambers JC, Frazer KA, Hinds DA, et al., 2006, Transcription factor 7-like-2 polymorphisms and risk of type 2 diabetes in Indian Asians and Northern Europeans, 79th Annual Scientific Session of the American-Heart-Association, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: 888-888, ISSN: 0009-7322
Chambers JC, Elliott P, Scott J, et al., 2006, Physical activity and risk of type 2 diabetes in UK Indian Asian and Northern European subjects in the London Life Sciences Population (LOLIPOP) study, 79th Annual Scientific Session of the American-Heart-Association, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: 894-895, ISSN: 0009-7322
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- Citations: 1
Chambers JC, Elliott P, Scott J, et al., 2006, Obesity and risk of Type 2 diabetes in UK Indian Asians and Northern Europeans in the London Life Sciences Population (LOLIPOP) Study, 79th Annual Scientific Session of the American-Heart-Association, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: 854-854, ISSN: 0009-7322
Chambers JC, Lim E, Elliott P, et al., 2006, The age and gender related patterns of insulin resistance in UK Indian Asians and Northern Europeans: The London Life Sciences Population (LOLIPOP) Study, 79th Annual Scientific Session of the American-Heart-Association, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: 902-903, ISSN: 0009-7322
Bogle RG, Sasikethan L, Jean-Marie J, et al., 2005, Effect of influenza vaccine on endothelial function in patients with type 2 diabetes, 27th Congress of the European-Society-of-Cardiology, Publisher: OXFORD UNIV PRESS, Pages: 261-261, ISSN: 0195-668X
Kapur A, Malik IS, Bagger JP, et al., 2005, The coronary artery revascularisation in diabetes (CARDia) trial: Background, aims, and design, AMERICAN HEART JOURNAL, Vol: 149, Pages: 13-19, ISSN: 0002-8703
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- Citations: 56
Chambers JC, Wander GS, Hooper J, et al., 2003, Plasma homocysteine and coronary heart disease mortality in India, Annual Scientific Conference of the British-Cardiac-Society, Publisher: B M J PUBLISHING GROUP, Pages: A58-A58, ISSN: 1355-6037
Chambers JC, Anand IS, Wander GS, et al., 2002, Plasma homocysteine and coronary heart disease mortality in India, American-Heart-Association Abstracts From Scientific Sessions, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: 732-733, ISSN: 0009-7322
Clarke R, Collins R, Lewington S, et al., 2002, Homocysteine and risk of ischemic heart disease and stroke -: A meta-analysis, JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, Vol: 288, Pages: 2015-2022, ISSN: 0098-7484
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- Citations: 1682
Spyrou N, Rosen SD, Fath-Ordoubadi F, et al., 2002, Myocardial beta-adrenoceptor density one month after acute myocardial infarction predicts left ventricular volumes at six months, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Vol: 40, Pages: 1216-1224, ISSN: 0735-1097
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- Citations: 39
Chambers JC, Kooner JS, 2002, Diabetes, insulin resistance and vascular disease among Indian Asians and Europeans., Semin Vasc Med, Vol: 2, Pages: 199-214, ISSN: 1528-9648
Indian Asians account for one-fifth of all cardiovascular deaths worldwide. Cardiovascular mortality in Indian Asians overseas is higher than in indigenous populations. Diabetes, insulin resistance, and related metabolic disturbances are more common among Indian Asians than Europeans and may account for up to 70% of major Q wave ECG abnormalities in Asians. Previous studies provide evidence that genetic and environmental factors, the latter including intrauterine growth retardation, reduced physical activity, increased weight, and dietary intake, contribute to the high prevalence of diabetes and insulin resistance in Asians. The importance of conventional coronary risk factors is emphasized by studies showing higher prevalence of cigarette smoking, hypertension, and hypercholesterolemia in migrant and urban Indians compared with rural Indians. Recent studies suggest that new risk factors, including C-reactive protein, homocysteine, and lipoprotein(a), are increased among Indian Asians compared with Europeans and may contribute to part of the excess cardiovascular risk in Asians. Further work is needed to identify the precise genetic and environmental mechanisms underlying increased vascular risk in Indian Asians. Clinical strategies must be developed that identify Indian Asians at increased risk and assess the effectiveness of treatment for insulin resistance, and other cardiovascular risk factors, in this racial group.
Chambers JC, Ahmed N, McGregor A, et al., 2001, Influenza vaccination induces vascular endothelial dysfunction in human subjects, CIRCULATION, Vol: 104, Pages: 561-561, ISSN: 0009-7322
Chambers JC, Kooner JS, 2001, The validity of coronary heart disease risk prediction models in UK Indian Asian, and European white men, EUROPEAN HEART JOURNAL, Vol: 22, Pages: 205-205, ISSN: 0195-668X
Chambers JC, Kooner JS, Ueland PM, et al., 2001, Investigation of the biologically active form of homocysteine in man, EUROPEAN HEART JOURNAL, Vol: 22, Pages: 129-129, ISSN: 0195-668X
Chambers JC, Kooner JS, Pepys MB, et al., 2001, Inflammatory mechanisms may contribute to increased coronary heart disease risk in UK Indian Asians, compared to European whites, EUROPEAN HEART JOURNAL, Vol: 22, Pages: 257-257, ISSN: 0195-668X
Chambers JC, Kooner JS, DeSwiet M, et al., 2001, Evidence for novel maternal mechanisms underlying pre-eclampsia, EUROPEAN HEART JOURNAL, Vol: 22, Pages: 459-459, ISSN: 0195-668X
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