Publications
517 results found
Nijjer S, Sen S, Cunha RPD, et al., 2013, INSTANTANEOUS WAVE–FREE RATIO (IFR) CAN DETECT IMPROVEMENT IN CORONARY HAEMODYNAMICS AFTER PCI, ISSN: 0735-1097
Sen S, Petraco R, Nijjer S, et al., 2013, THE TRANS–STENOTIC PRESSURE GRADIENT DURING THE DIASTOLIC WAVE–FREE PERIOD IS PROPORTIONAL TO FLOW: THE PHYSIOLOGICAL BASIS OF THE INSTANT–WAVE–FREE RATIO, ISSN: 0735-1097
Sen S, Asrress KN, Nijjer S, et al., 2013, Diagnostic Classification of the Instantaneous Wave-Free Ratio Is Equivalent to Fractional Flow Reserve and Is Not Improved With Adenosine Administration, Journal of the American College of Cardiology, Vol: 61, Pages: 1409-1420, ISSN: 0735-1097
Norrington KD, Turner HK, Barakat MF, et al., 2012, Prognostic Utility of the Hemoglobin/Hematocrit Equation for Estimating Plasma Volume Changes During Hospitalization for Acute Decompensated Heart Failure, CIRCULATION, Vol: 126, ISSN: 0009-7322
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- Citations: 1
Ghosh AK, Hardy RJ, Francis DP, et al., 2012, The Effect of Mid-life Blood Pressure Change and Anti-Hypertensive Treatment on Subsequent Left Ventricular Mass - A Life Course Approach, CIRCULATION, Vol: 126, ISSN: 0009-7322
Konstantinou K, Aung N, Norrington K, et al., 2012, Evolving Iron Deficiency Confers Most of the Adversity Associated with a Temporal Rise in Red Cell Distribution Width, is More Ominous than a Falling Hemoglobin, and Blunts Left Ventricular Long Axis Function in Chronic Heart Failure, CIRCULATION, Vol: 126, ISSN: 0009-7322
Khamis R, Johns M, Thom S, et al., 2012, The ASCOT Anti-oxidised LDL Antibodies Substudy, IgG Anti-malondialdehyde-ldl Antibodies are Independent Predictors of Protection From Cardiovascular Events in a Substudy of the Anglo-scandinavian Cardiac Outcomes Trial, CIRCULATION, Vol: 126, ISSN: 0009-7322
Sen S, Davies JE, Malik IS, et al., 2012, Why Does Primary Angioplasty Not Work in Registries? Quantifying the Susceptibility of Real-World Comparative Effectiveness Data to Allocation Bias, CIRCULATION-CARDIOVASCULAR QUALITY AND OUTCOMES, Vol: 5, Pages: 759-766, ISSN: 1941-7705
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- Citations: 14
Sen S, Petraco R, Nijjer S, et al., 2012, The Diastolic Wave-Free Period Is The Most Suitable Period In The Cardiac Cycle For The Assessment Of A Coronary Stenosis: Implications For The Accurate Calculation Of The Instantaneous Wave-Free Ratio (iFR), Transcatheter Cardiovascular Therapeutics (TCT) Symposium, Publisher: ELSEVIER SCIENCE INC, Pages: B68-B68, ISSN: 0735-1097
Al-Lamee R, Broyd C, Parker J, et al., 2012, Influence Of Gender On Clinical Outcomes Following Transcatheter Aortic Valve Implantation: Results From The UK TAVI Registry On Behalf Of The UK TAVI Steering Group And The National Institute For Cardiovascular Outcomes Research, Transcatheter Cardiovascular Therapeutics (TCT) Symposium, Publisher: ELSEVIER SCIENCE INC, Pages: B30-B30, ISSN: 0735-1097
Sen S, Asrress K, Petraco R, et al., 2012, Does Adenosine Administration Improve Diagnostic Classification Of The Instantaneous Wave-Free Ratio (iFR)?, Transcatheter Cardiovascular Therapeutics (TCT) Symposium, Publisher: ELSEVIER SCIENCE INC, Pages: B69-B69, ISSN: 0735-1097
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- Citations: 2
Sen S, Nijjer S, Petraco R, et al., 2012, The Instantaneous Wave-Free Ratio (iFR) and Fractional Flow Reserve (FFR) Have Equivalent Diagnostic Categorisation When Compared To Flow Based Indices, Transcatheter Cardiovascular Therapeutics (TCT) Symposium, Publisher: ELSEVIER SCIENCE INC, Pages: B68-B69, ISSN: 0735-1097
Foin N, Sen S, Petraco R, et al., 2012, Investigation of Fractional Flow Reserve Correlation with Direct Anatomical Parameters Using a Percutaneous Model of Coronary Artery Stenosis, Transcatheter Cardiovascular Therapeutics (TCT) Symposium, Publisher: ELSEVIER SCIENCE INC, Pages: B67-B67, ISSN: 0735-1097
Ghosh AK, Hardy RJ, Francis DP, et al., 2012, Is it time for a new look at the 'watch and wait' approach-mid-life antihypertensive treatment may not normalize left ventricular mass in spite of controlled blood pressure, JOURNAL OF HUMAN HYPERTENSION, Vol: 26, Pages: 616-616, ISSN: 0950-9240
Surendran P, Vangjeli C, McCarthy N, et al., 2012, Genome-wide association analysis identifies the MTHFR-CLCN6-NPPA-NPPB gene cluster as an important influence on BNP levels-implications for the use of BNP levels in the diagnosis and therapeutic monitoring of heart failure-an ASCOT sub study, JOURNAL OF HUMAN HYPERTENSION, Vol: 26, Pages: 620-620, ISSN: 0950-9240
Kyriacou A, Whinnett ZI, Sen S, et al., 2012, Improvement in Coronary Blood Flow Velocity With Acute Biventricular Pacing Is Predominantly Due to an Increase in a Diastolic Backward-Travelling Decompression (Suction) Wave, CIRCULATION, Vol: 126, Pages: 1334-+, ISSN: 0009-7322
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- Citations: 28
Davies JE, Alastruey J, Francis DP, et al., 2012, Attenuation of Wave Reflection by Wave Entrapment Creates a "Horizon Effect" in the Human Aorta, HYPERTENSION, Vol: 60, Pages: 778-+, ISSN: 0194-911X
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- Citations: 61
Raphael CE, Salukhe TV, Barron A, et al., 2012, Effect of mortality rate on lifespan gain from implantable cardioverter-defibrillators: analysis of existing and need for further randomised controlled trials, Congress of the European-Society-of-Cardiology (ESC), Publisher: OXFORD UNIV PRESS, Pages: 542-542, ISSN: 0195-668X
Ghosh AK, Hardy RJ, Francis DP, et al., 2012, High systolic blood pressure and increased rate of rise of blood pressure in mid-life predict impaired diastolic function in the elderly (The MRC NSHD), Eur Heart J, Pages: 361-361
Kyriacou A, Pabari PA, Whinnett ZI, et al., 2012, Fully Automatable, Reproducible, Noninvasive Simple Plethysmographic Optimization: Proof of Concept and Potential for Implantability, PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY, Vol: 35, Pages: 948-960, ISSN: 0147-8389
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- Citations: 9
Finegold JA, Manisty CH, Cecaro F, et al., 2012, Choosing between velocity-time-integral ratio and peak velocity ratio for calculation of the dimensionless index (or aortic valve area) in serial follow-up of aortic stenosis, International Journal of Cardiology
It remains unclear which echocardiographic measure is most suitable for serial measurement in real-world aortic stenosis (AS) follow-up. We determine whether the dimensionless index (DI) between aortic valve and left ventricular outflow tract velocities is measured more consistently using velocity-time-integral (VTI) or peak velocities (V(peak)) in real life.METHODS:Serial echocardiograms acquired within 6months in subjects with AS were analysed with blinding, to compare the variability over time of DI calculated using V(peak), with that of DI calculated using VTI.RESULTS:Paired echocardiograms, acquired on average 72days apart, were analysed from 70 patients with a range of severities of AS (59% severe). DI, calculated using either V(peak) or VTI, did not significantly change over this short time. Coefficient of variation was significantly better when DI was calculated using V(peak) than VTI (12.6 versus 25.4%, p<0.0001). The variabilities of mean and peak trans-aortic valve 4v(2) and left ventricular outflow tract VTI were no better: 26.9%, 19.1% and 22.1% respectively.CONCLUSIONS:Serially-followed variables require minimal noise to maximise detection of genuine change. For AS surveillance, calculating DI - or effective orifice area - from the ratio of V(peak) rather than VTIs would reduce 95% confidence intervals from ±51% to a still-disappointing ±25%. Guidelines recommend noisy surveillance measures, causing conscientious echocardiographers to 'peek' at previous values, and impairing clinicians' faith in echocardiographically-observed changes when making clinical decisions. For us in echocardiography to improve our ability to contribute to AS follow-up requires us to first acknowledge and discuss this honestly.
Jabbour RJ, Husain S, Zaman N, et al., 2012, MULTICENTRE VALIDATION OF THE ADVERSE PROGNOSTIC IMPLICATIONS OF DECLINING SERUM ALBUMIN LEVELS IN CHRONIC HEART FAILURE, Annual Conference of the British-Cardiovascular-Society (BCS), Publisher: B M J PUBLISHING GROUP, Pages: A9-A9, ISSN: 1355-6037
Pabari PA, Moraldo M, Hughes AD, et al., 2012, VALIDATING MARKERS OF MECHANICAL DYSSYNCHRONY BY EXPERIMENTAL MANIPULATION OF INTERVENTRICULAR TIMINGS: WHAT IS NEEDED TO MAKE THEM A REASONABLE PROSPECT FOR CARDIAC RESYNCHRONISATION THERAPY SELECTION?, Annual Conference of the British-Cardiovascular-Society (BCS), Publisher: B M J PUBLISHING GROUP, Pages: A5-A5, ISSN: 1355-6037
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- Citations: 1
Sen S, Escaned J, Malik I, et al., 2012, DEVELOPMENT AND VALIDATION OF A NOVEL PRESSURE-ONLY INTRA-CORONARY INDEX OF CORONARY STENOSIS SEVERITY, Annual Conference of the British-Cardiovascular-Society (BCS), Publisher: B M J PUBLISHING GROUP, Pages: A13-A13, ISSN: 1355-6037
Kyriacou A, Whinnett ZI, Sen S, et al., 2012, IMPROVEMENT IN CORONARY BLOOD FLOW WITH ACUTE BIVENTRICULAR PACING IS PREDOMINANTLY DUE TO AN INCREASE IN A DIASTOLIC BACKWARD-TRAVELLING DECOMPRESSION (SUCTION) WAVE, Annual Conference of the British-Cardiovascular-Society (BCS), Publisher: B M J PUBLISHING GROUP, Pages: A7-A8, ISSN: 1355-6037
Hunter RJ, Berriman TJ, Diab I, et al., 2012, A RANDOMISED CONTROLLED TRIAL OF CATHETER ABLATION VS MEDICAL TREATMENT OF ATRIAL FIBRILLATION IN HEART FAILURE (THE CAMTAF TRIAL), Annual Conference of the British-Cardiovascular-Society (BCS), Publisher: B M J PUBLISHING GROUP, Pages: A34-A34, ISSN: 1355-6037
Pabari PA, Kyriacou A, Wright I, et al., 2012, SIMULTANEOUS INVASIVE PRESSURE AND FLOW MEASUREMENTS DURING ATRIOVENTRICULAR DELAY IMPROVEMENT REVEAL A COMPENSATORY PERIPHERAL VASODILATOR RESPONSE WHICH ATTENUATES THE INITIAL BLOOD PRESSURE INCREMENT: IMPLICATIONS FOR THE DESIGN OF OPTIMISATION PROTOCOLS, Annual Conference of the British-Cardiovascular-Society (BCS), Publisher: BMJ PUBLISHING GROUP, Pages: A5-A6, ISSN: 1355-6037
Ghosh AK, Et al, 2012, Time for a review of the “watch and wait” strategy for young borderline-hypertensives?, Heart 2012;98:A77
Ghosh AK, Et al, 2012, Increase in left ventricular mass in type 2 diabetes is dependent on duration of diabetes, Heart 2012;98:A77
Kyriacou A, Wa MLK, Pabari P, et al., 2012, SHOULD CURRENT MODALITIES OF VV OPTIMISATION BE TRUSTED? AN ASSESSMENT OF THE INTERNAL VALIDITY OF ECHOCARDIOGRAPHIC, ELECTROCARDIOGRAPHIC AND HAEMODYNAMIC MODALITIES OF OPTIMISATION, Annual Conference of the British-Cardiovascular-Society (BCS), Publisher: B M J PUBLISHING GROUP, Pages: A8-A8, ISSN: 1355-6037
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