Imperial College London

Emeritus ProfessorJeremyNicholson

Faculty of MedicineDepartment of Metabolism, Digestion and Reproduction

Emeritus Professor of Biological Chemistry
 
 
 
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Contact

 

+44 (0)20 7594 3195j.nicholson Website

 
 
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Assistant

 

Ms Wendy Torto +44 (0)20 7594 3225

 
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Location

 

Office no. 665Sir Alexander Fleming BuildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{NICHOLSON:1983:10.1111/j.1469-7998.1983.tb06111.x,
author = {NICHOLSON, JK and OSBORN, D},
doi = {10.1111/j.1469-7998.1983.tb06111.x},
journal = {Journal of Zoology},
pages = {99--118},
title = {Kidney lesions in pelagic seabirds with high tissue levels of cadmium and mercury},
url = {http://dx.doi.org/10.1111/j.1469-7998.1983.tb06111.x},
volume = {200},
year = {1983}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - Light and electron microscopic techniques were employed to examine the kidneys of three species of pelagic seabird which had high tissue cadmium and mercury levels. Direct examination and comparison with the kidneys of cadmium and mercury dosed starlings showed that the seabirds had patchy nephrotoxic kidney lesions. It was suggested that these lesions were due to natural exposure of the animals to high levels of metals, particularly cadmium through their diet. Pathological features included necrosis and degeneration of the proximal tubular epithelium together with the direct observation of obstruction of the more distal neprhon segments by necrotic cellular debris. Abnormalities of the glomerular podocytes and Bowman's capsule cells were also observed. There was a high degree of similarity between the type and distribution of kidney lesions in the seabirds and the laboratory metal dosed starlings. The significance of this kidney damage and its possible effects on the birds survival prospects are discussed. Copyright © 1983, Wiley Blackwell. All rights reserved
AU - NICHOLSON,JK
AU - OSBORN,D
DO - 10.1111/j.1469-7998.1983.tb06111.x
EP - 118
PY - 1983///
SN - 0952-8369
SP - 99
TI - Kidney lesions in pelagic seabirds with high tissue levels of cadmium and mercury
T2 - Journal of Zoology
UR - http://dx.doi.org/10.1111/j.1469-7998.1983.tb06111.x
VL - 200
ER -