Imperial College London

Emeritus ProfessorJeremyNicholson

Faculty of MedicineDepartment of Metabolism, Digestion and Reproduction

Emeritus Professor of Biological Chemistry
 
 
 
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Contact

 

+44 (0)20 7594 3195j.nicholson Website

 
 
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Assistant

 

Ms Wendy Torto +44 (0)20 7594 3225

 
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Location

 

Office no. 665Sir Alexander Fleming BuildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Nicholson:1983,
author = {Nicholson, JK and Kendall, MD},
journal = {Journal of Anatomy},
pages = {145--156},
title = {The fine structure of dark or intercalated cells from the distal and collecting tubules of avian kidneys},
volume = {136},
year = {1983}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - Dark or intercalated cells were identified in the terminal portion of the distal tubules and in the intralobular collecting tubules of four species of birds. The morphological features of these cells varied only slightly from species to species and were very similar to cells found in topographically analogous regions of mammalian nephrons. Characteristic vesicles usually filled the apical region of the dark cells and were often in direct continuity with the apical plasma membrane which was frequently thrown into elaborate folds, microvilli and microplicae. Observations suggested that the cells might be involved in some form of cyclical secretory activity. The similarity in structure between avian and mammalian dark cells suggested that they might perform similar functions and that the study of avian cells might aid the elucidation of the mammalian cell function. The possible function of the avian cells were discussed in relation to physiological studies in mammalian kidneys and it was suggested that they might be involved with proton and potassium pumping and control of urinary buffer concentrations.
AU - Nicholson,JK
AU - Kendall,MD
EP - 156
PY - 1983///
SN - 0021-8782
SP - 145
TI - The fine structure of dark or intercalated cells from the distal and collecting tubules of avian kidneys
T2 - Journal of Anatomy
VL - 136
ER -