Imperial College London
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Professor José R Penadés

Faculty of Medicine, Department of Infectious Disease

Director MRC Centre for Molecular Bacteriology & Infection
 
 
 
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Contact

 

+44 (0)20 7594 8533j.penades Website

 
 
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Assistant

 

Mrs Anna Lee +44 (0)20 7594 2954

 
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Location

 

Flowers buildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@inbook{Haag:2019:10.1128/9781683670131.ch46,
author = {Haag, AF and Ross, Fitzgerald J and Penadés, JR},
booktitle = {Gram-Positive Pathogens},
doi = {10.1128/9781683670131.ch46},
pages = {731--746},
title = {Staphylococcus aureus in animals},
url = {http://dx.doi.org/10.1128/9781683670131.ch46},
year = {2019}
}
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RIS format (EndNote, RefMan)

TY  - CHAP
AB  - The genus Staphylococcus currently comprises 81 species and subspecies (https://www.dsmz.de/bacterial-diversity/prokaryotic-nomenclature-up-to-date/prokaryotic-nomenclature-up-to-date.html), and most members of the genus are mammalian commensals or opportunistic pathogens that colonize niches such as skin, nares, and diverse mucosal membranes. Several species are of significant medical or veterinary importance. Staphylococcus pseudintermedius (1) is a leading cause of pyoderma in dogs and is considered to be a significant reservoir of antimicrobial resistance factors for the genus (2, 3). S. pseudintermedius is very similar to Staphylococcus intermedius and can be distinguished from other coagulase-positive staphylococci by positive arginine dihydrolase and acid production from β-gentiobiose and d-mannitol (4) or by using a multiplex-PCR approach targeting the nuclease gene nuc (5). Staphylococcus saprophyticus is the second leading cause of uncomplicated urinary tract infections (6). While Staphylococcus epidermidis is a normal component of the epidermal microbiota, it is a leading cause of biofilm contamination of medical devices (7). The most promiscuous and most significant human pathogenic staphylococcal species is Staphylococcus aureus, which is the causal agent of a variety of disease symptoms that can range from cosmetic to lethal manifestations. S. aureus is distinguished from most members of the genus by its abundant production of secreted coagulase, an enzyme which converts serum fibrinogen to fibrin and promotes clotting. However, the S. intermedius group and some strains of Staphylococcus lugdunensis have coagulase activity (5, 8, 9).
AU  - Haag,AF
AU  - Ross,Fitzgerald J
AU  - Penadés,JR
DO  - 10.1128/9781683670131.ch46
EP  - 746
PY  - 2019///
SN  - 9781683670124
SP  - 731
TI  - Staphylococcus aureus in animals
T1  - Gram-Positive Pathogens
UR  - http://dx.doi.org/10.1128/9781683670131.ch46
ER  -
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