Imperial College London

DrJamesPeters

Faculty of MedicineDepartment of Immunology and Inflammation

Clinical Reader in Rheumatology
 
 
 
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Contact

 

j.peters

 
 
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Location

 

ICTEM buildingHammersmith Campus

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Summary

 

Summary


About me

I am a UKRI Innovation Fellow at Health Data Research UK and Clinical Reader in Rheumatology. I moved to Imperial College as a Group Leader in 2019.

My group’s research lies at the interface of molecular epidemiology, computational biology and clinical medicine. Our focus is understanding the molecular and cellular basis of immune-mediated inflammatory diseases using a combination of genomics, transcriptomics and proteomics. We employ a wide range of techniques including longitudinal molecular profiling, polygenic risk scores, and Mendelian randomisation, leveraging both our own in-house datasets and also publically available resources (eg GWAS summary statistics, UK Biobank).

Selected Publications

Journal Articles

Klaric L, Gisby JS, Papadaki A, et al., 2021, Mendelian randomisation identifies alternative splicing of the FAS death receptor as a mediator of severe COVID-19., Medrxiv

Gaziano L, Giambartolomei C, Pereira AC, et al., 2021, Actionable druggable genome-wide Mendelian randomization identifies repurposing opportunities for COVID-19., Nat Med, Vol:27, Pages:668-676

Gisby J, Clarke CL, Medjeral-Thomas N, et al., 2021, Longitudinal proteomic profiling of dialysis patients with COVID-19 reveals markers of severity and predictors of death, Elife, Vol:10, ISSN:2050-084X

Folkersen L, Gustafsson S, Wang Q, et al., 2020, Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals, Nature Metabolism, Vol:2, ISSN:2522-5812, Pages:1135-1148

Tarkin JM, Wall C, Gopalan D, et al., 2020, Novel approach to imaging active takayasu arteritis using somatostatin receptor positron emission tomography/magnetic resonance imaging., Circulation-Cardiovascular Imaging, Vol:13, ISSN:1941-9651, Pages:1-3

Lyons PA, Peters JE, Alberici F, et al., 2019, Genome-wide association study of eosinophilic granulomatosis with polyangiitis reveals genomic loci stratified by ANCA status, Nature Communications, Vol:10, ISSN:2041-1723

Richard AC, Peters JE, Savinykh N, et al., 2018, Reduced monocyte and macrophage TNFSF15/TL1A expression is associated with susceptibility to inflammatory bowel disease, PLOS Genetics, Vol:14, ISSN:1553-7390

Sun BB, Maranville JC, Peters JE, et al., 2018, Genomic atlas of the human plasma proteome, Nature, Vol:558, ISSN:0028-0836, Pages:73-79

Peters JE, Lyons PA, Lee JC, et al., 2016, Insight into genotype-phenotype associations through eQTL mapping in multiple cell types in health and immune-mediated disease, PLOS Genetics, Vol:12, ISSN:1553-7390, Pages:1-29

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