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BibTex format

@inbook{Posma:2018:10.1016/B978-0-12-809633-8.20254-9,
author = {Posma, JM},
booktitle = {Encyclopedia of Bioinformatics and Computational Biology},
doi = {10.1016/B978-0-12-809633-8.20254-9},
editor = {Cannataro and Gaeta and Gribskov and Asif, Khan and Nakai and Ranganathan and Schonbach},
title = {Metabolic profiling},
url = {http://dx.doi.org/10.1016/B978-0-12-809633-8.20254-9},
year = {2018}
}

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TY  - CHAP
AB  - Metabolic profiling involves the measurement of metabolites, small molecules under 1 kDa in weight, in biological fluids such as plasma/serum and urine or in tissue samples using high-throughput spectroscopic and spectrometric technologies. It contributes phenotypic information which cannot be directly obtained from other omic platforms that can be associated with disease diagnosis and prognosis, and provide mechanistic understanding of disease aetiology and drug treatments. This Chapter provides background on the data generated by Nuclear Magnetic Resonance spectroscopy and hyphenated Mass Spectrometry techniques, bioinformatic and statistical methods used to analyse these data and discusses bottlenecks in data processing, analysis and interpretation.
AU  - Posma,JM
DO  - 10.1016/B978-0-12-809633-8.20254-9
PY  - 2018///
TI  - Metabolic profiling
T1  - Encyclopedia of Bioinformatics and Computational Biology
UR  - http://dx.doi.org/10.1016/B978-0-12-809633-8.20254-9
ER  -

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Dr Joram M. Posma PhD MSc B AS MRSC

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