Imperial College London
Portrait Picture

ProfessorJenniferQuint

Faculty of Medicine, School of Public Health

Professor of Respiratory Epidemiology
 
 
 
//

Contact

 

+44 (0)20 7594 8821j.quint

 
 
//

Location

 

.922Sir Michael Uren HubWhite City Campus

//

Summary

 

Publications

Citation

BibTex format

@article{Axson:2018:10.1007/s10096-018-3315-6,
author = {Axson, EL and Bloom, CI and Quint, JK},
doi = {10.1007/s10096-018-3315-6},
journal = {European Journal of Clinical Microbiology and Infectious Diseases},
pages = {1795--1803},
title = {Nontuberculous mycobacterial disease managed within UK primary care, 2006-2016},
url = {http://dx.doi.org/10.1007/s10096-018-3315-6},
volume = {37},
year = {2018}
}
Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Previous UK studies investigating nontuberculous mycobacteria have been limited to reporting isolation from culture, not burden of disease. We assessed the burden of nontuberculous mycobacterial disease (NTMD) in UK primary care from 2006 to 2016. Using electronic healthcare records, we identified patients with NTMD using a strict definition including patients with guideline-directed treatment/monitoring. We described treatment regimens and incidence/prevalence in the general population and in patients with underlying chronic respiratory diseases. Incidence of primary care-managed NTMD in the general population decreased (2006 to 2016 rates per 100,000 person-years, 3.85 to 1.28). Average annual prevalence of NTMD in the general population was 6.38 per 100,000. Around 85% were taking antimycobacterial therapy; 53.2% were taking a guideline-recommended regimen. Incidence of NTMD in patients with respiratory disease decreased (2006 to 2016 rates per 100,000 person-years, 12.5 to 7.40). Average annual prevalence of NTMD in patients with respiratory disease was 27.7 per 100,000. This is the first UK study using nationally representative data to investigate the burden of NTMD managed within primary care. Incidence and prevalence of managed NTMD within primary care is gradually declining. Increasing complexity in the management of NTMD may be driving a shift in care to secondary settings.
AU  - Axson,EL
AU  - Bloom,CI
AU  - Quint,JK
DO  - 10.1007/s10096-018-3315-6
EP  - 1803
PY  - 2018///
SN  - 0934-9723
SP  - 1795
TI  - Nontuberculous mycobacterial disease managed within UK primary care, 2006-2016
T2  - European Journal of Clinical Microbiology and Infectious Diseases
UR  - http://dx.doi.org/10.1007/s10096-018-3315-6
UR  - http://hdl.handle.net/10044/1/61689
VL  - 37
ER  -
Download