Imperial College London
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ProfessorJenniferQuint

Faculty of Medicine, School of Public Health

Professor of Respiratory Epidemiology
 
 
 
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Contact

 

+44 (0)20 7594 8821j.quint

 
 
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Location

 

.922Sir Michael Uren HubWhite City Campus

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Summary

 

Publications

Citation

BibTex format

@article{Gulea:2019:10.1016/j.ijcard.2019.04.087,
author = {Gulea, C and Zakeri, R and Quint, JK},
doi = {10.1016/j.ijcard.2019.04.087},
journal = {International Journal of Cardiology},
pages = {113--118},
title = {Impact of chronic obstructive pulmonary disease on readmission after hospitalization for acute heart failure: A nationally representative US cohort study},
url = {http://dx.doi.org/10.1016/j.ijcard.2019.04.087},
volume = {290},
year = {2019}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - BackgroundPatients hospitalized for heart failure (HF) are at high risk of readmission. Chronic obstructive pulmonary disease (COPD) is one of the most prevalent comorbidities in this population. However, few data and only small studies describe the impact of COPD on the risk of readmission.Methods and resultsHospitalizations for HF were identified in the 2012 National Readmissions Database. We compared clinical characteristics and the risk of all-cause, cardiovascular (CV) and respiratory-related readmission for patients with and without COPD. We included 225,160 patients hospitalized for HF among whom 54,953 had comorbid COPD. Patients with COPD were younger (median age 76years COPD versus 77years without COPD; p<0.001), had a higher burden of comorbidity and were more frequently male (53% versus 49%, p<0.001). Thirty-day all-cause readmission risk was two-fold greater in patients with COPD compared to those without COPD (adjusted HR 2.02, 95%CI 1.97–2.08). Most readmissions were attributed to a CV cause, though fewer patients with COPD had a CV admission (49% versus 51% without COPD). COPD was independently associated with significantly more frequent unplanned respiratory-related readmission (adjusted HR 2.90, 95%CI 2.68–3.15) as well as CV readmission risk (adjusted HR 1.92, 95%CI 1.85–1.99).ConclusionsIn patients hospitalized for HF, most readmissions are due to a CV cause. However, patients with comorbid COPD are at a significantly elevated risk of respiratory in addition to CV-related readmission. These data stress the importance of a multidisciplinary management approach, including optimization of non-CV conditions, in order to reduce readmissions post index HF hospitalization.
AU  - Gulea,C
AU  - Zakeri,R
AU  - Quint,JK
DO  - 10.1016/j.ijcard.2019.04.087
EP  - 118
PY  - 2019///
SN  - 0167-5273
SP  - 113
TI  - Impact of chronic obstructive pulmonary disease on readmission after hospitalization for acute heart failure: A nationally representative US cohort study
T2  - International Journal of Cardiology
UR  - http://dx.doi.org/10.1016/j.ijcard.2019.04.087
UR  - http://hdl.handle.net/10044/1/69509
VL  - 290
ER  -
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