Imperial College London
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ProfessorJenniferQuint

Faculty of Medicine, School of Public Health

Professor of Respiratory Epidemiology
 
 
 
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Contact

 

+44 (0)20 7594 8821j.quint

 
 
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Location

 

.922Sir Michael Uren HubWhite City Campus

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Summary

 

Publications

Citation

BibTex format

@article{Whittaker:2020,
author = {Whittaker, H and Connell, O and Campbell, J and Elbehairy, A and Hopkinson, N and Quint, J},
journal = {Chest},
pages = {276--285},
title = {Eligibility for lung volume reduction surgery in chronic obstructive pulmonary disease patients identified in a UK primary care setting},
url = {https://www.sciencedirect.com/science/article/pii/S0012369219313911?via%3Dihub},
volume = {157},
year = {2020}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - BackgroundAlthough lung volume reduction surgery (LVRS) improves survival in appropriately selected patients with Chronic Obstructive Pulmonary Disease (COPD), few procedures are performed. The National Institute for Clinical and Healthcare Excellence recently recommended a more systematic approach to identifying potential candidates. We investigated LVRS referrals from a UK primary care population and aimed to establish an accurate estimate of eligible patients and determine a strategy for identifying potential candidates systematically.MethodsClinical Practice Research Datalink (CPRD) GOLD (a primary care database), linked Hospital Episode Statistics (HES) inpatient and Diagnostic Imaging Dataset (DID) were used. COPD patients who had undergone LVRS, patients who met basic eligibility criteria for further screening for LVRS, and patients meeting a more stringent eligibility criteria were identified from April 2012 to September 2015. Thoracic CT, pulmonary rehabilitation status, referral to respiratory outpatient clinics, and AECOPD requiring hospitalisation were compared between actual LVRS recipients and potentially eligible patients. ResultsAmong 73,697 COPD patients included, 36 (0.05%) received LVRS, 5,984 (8.1%) met basic eligibility criteria, and 159 (0.2%) met more stringent eligibility criteria. LVRS recipients were younger (mean(SD) age: 64(9.2) years) compared to the stringently eligible patients (69(8.9) years) (p=0.01). Few patients meeting stringent eligibility criteria (6.9%) had a CT thorax in the preceding 3 years or been referred for assessment in secondary care. ConclusionsA substantial unmet need exists among COPD patients who could potentially benefit from a lung volume reduction procedure but who are not being investigated or referred to consider this possibility.
AU  - Whittaker,H
AU  - Connell,O
AU  - Campbell,J
AU  - Elbehairy,A
AU  - Hopkinson,N
AU  - Quint,J
EP  - 285
PY  - 2020///
SN  - 0012-3692
SP  - 276
TI  - Eligibility for lung volume reduction surgery in chronic obstructive pulmonary disease patients identified in a UK primary care setting
T2  - Chest
UR  - https://www.sciencedirect.com/science/article/pii/S0012369219313911?via%3Dihub
UR  - http://hdl.handle.net/10044/1/72221
VL  - 157
ER  -
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