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@article{Mansfield:2021:10.1016/S2589-7500(21)00017-0,
author = {Mansfield, KE and Mathur, R and Tazare, J and Henderson, AD and Mulick, AR and Carreira, H and Matthews, AA and Bidulka, P and Gayle, A and Forbes, H and Cook, S and Wong, AYS and Strongman, H and Wing, K and Warren-Gash, C and Cadogan, SL and Smeeth, L and Hayes, JF and Quint, JK and McKee, M and Langan, SM},
doi = {10.1016/S2589-7500(21)00017-0},
journal = {The Lancet Digital Health},
pages = {e217--e230},
title = {Indirect acute effects of the COVID-19 pandemic on physical and mental health in the UK: a population-based study},
url = {http://dx.doi.org/10.1016/S2589-7500(21)00017-0},
volume = {3},
year = {2021}
}

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TY  - JOUR
AB  - BACKGROUND: There are concerns that the response to the COVID-19 pandemic in the UK might have worsened physical and mental health, and reduced use of health services. However, the scale of the problem is unquantified, impeding development of effective mitigations. We aimed to ascertain what has happened to general practice contacts for acute physical and mental health outcomes during the pandemic. METHODS: Using de-identified electronic health records from the Clinical Research Practice Datalink (CPRD) Aurum (covering 13% of the UK population), between 2017 and 2020, we calculated weekly primary care contacts for selected acute physical and mental health conditions: anxiety, depression, self-harm (fatal and non-fatal), severe mental illness, eating disorder, obsessive-compulsive disorder, acute alcohol-related events, asthma exacerbation, chronic obstructive pulmonary disease exacerbation, acute cardiovascular events (cerebrovascular accident, heart failure, myocardial infarction, transient ischaemic attacks, unstable angina, and venous thromboembolism), and diabetic emergency. Primary care contacts included remote and face-to-face consultations, diagnoses from hospital discharge letters, and secondary care referrals, and conditions were identified through primary care records for diagnoses, symptoms, and prescribing. Our overall study population included individuals aged 11 years or older who had at least 1 year of registration with practices contributing to CPRD Aurum in the specified period, but denominator populations varied depending on the condition being analysed. We used an interrupted time-series analysis to formally quantify changes in conditions after the introduction of population-wide restrictions (defined as March 29, 2020) compared with the period before their introduction (defined as Jan 1, 2017 to March 7, 2020), with data excluded for an adjustment-to-restrictions period (March 8-28). FINDINGS: The overall population included 9863903 individuals
AU  - Mansfield,KE
AU  - Mathur,R
AU  - Tazare,J
AU  - Henderson,AD
AU  - Mulick,AR
AU  - Carreira,H
AU  - Matthews,AA
AU  - Bidulka,P
AU  - Gayle,A
AU  - Forbes,H
AU  - Cook,S
AU  - Wong,AYS
AU  - Strongman,H
AU  - Wing,K
AU  - Warren-Gash,C
AU  - Cadogan,SL
AU  - Smeeth,L
AU  - Hayes,JF
AU  - Quint,JK
AU  - McKee,M
AU  - Langan,SM
DO  - 10.1016/S2589-7500(21)00017-0
EP  - 230
PY  - 2021///
SN  - 2589-7500
SP  - 217
TI  - Indirect acute effects of the COVID-19 pandemic on physical and mental health in the UK: a population-based study
T2  - The Lancet Digital Health
UR  - http://dx.doi.org/10.1016/S2589-7500(21)00017-0
UR  - https://www.ncbi.nlm.nih.gov/pubmed/33612430
UR  - http://hdl.handle.net/10044/1/87700
VL  - 3
ER  -

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