Imperial College London
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ProfessorJenniferQuint

Faculty of Medicine, School of Public Health

Professor of Respiratory Epidemiology
 
 
 
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Contact

 

+44 (0)20 7594 8821j.quint

 
 
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Location

 

.922Sir Michael Uren HubWhite City Campus

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Summary

 

Publications

Citation

BibTex format

@article{Whittaker:2021:10.1101/2021.04.09.21255199,
author = {Whittaker, HR and Gulea, C and Koteci, A and Kallis, C and Morgan, AD and Iwundu, C and Weeks, M and Gupta, R and Quint, JK},
doi = {10.1101/2021.04.09.21255199},
title = {Post-acute COVID-19 sequelae in cases managed in the community or hospital in the UK: a population based study},
url = {http://dx.doi.org/10.1101/2021.04.09.21255199},
year = {2021}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - <jats:title>Abstract</jats:title><jats:sec><jats:title>Objective</jats:title><jats:p>To compare post-COVID-19 sequelae between hospitalised and non-hospitalised individuals</jats:p></jats:sec><jats:sec><jats:title>Design</jats:title><jats:p>Population-based cohort study</jats:p></jats:sec><jats:sec><jats:title>Setting</jats:title><jats:p>1,383 general practices in England contributing to Clinical Practice Research Database Aurum</jats:p></jats:sec><jats:sec><jats:title>Participants</jats:title><jats:p>46,687 COVID-19 cases diagnosed between 1<jats:sup>st</jats:sup> August to 17<jats:sup>th</jats:sup> October 2020 (45.4% male; mean age 40), either hospitalised within two weeks of diagnosis or non-hospitalised, and followed-up for a maximum of three months.</jats:p></jats:sec><jats:sec><jats:title>Main outcome measures</jats:title><jats:p>Event rates of new symptoms, diseases, prescriptions and healthcare utilisation in hospitalised and non-hospitalised individuals, with between-group comparison using Cox regression. Outcomes compared at 6 and 12 months prior to index date, equating to first UK wave and pre-pandemic. Non-hospitalised group outcomes stratified by age and sex.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>45,272 of 46,687 people were non-hospitalised; 1,415 hospitalised. Hospitalised patients had higher rates of 13/26 symptoms and 11/19 diseases post-COVID-19 than the community group, received more prescriptions and utilised more healthcare. The largest differences were noted for rates per 100,000 person-weeks [95%CI] of <jats:italic>breathlessness:</jats:italic> 536 [432 to 663] v. 85 [77 to 93]; <jats:italic>joint pain:</jats:italic> 295 [221 to 392] v. 168 [158 to 179]
AU  - Whittaker,HR
AU  - Gulea,C
AU  - Koteci,A
AU  - Kallis,C
AU  - Morgan,AD
AU  - Iwundu,C
AU  - Weeks,M
AU  - Gupta,R
AU  - Quint,JK
DO  - 10.1101/2021.04.09.21255199
PY  - 2021///
TI  - Post-acute COVID-19 sequelae in cases managed in the community or hospital in the UK: a population based study
UR  - http://dx.doi.org/10.1101/2021.04.09.21255199
ER  -
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