Imperial College London
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DrJesusRodriguez Manzano

Faculty of Medicine, Department of Infectious Disease

Senior Lecturer in Diagnostics for Infectious Disease
 
 
 
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Contact

 

j.rodriguez-manzano

 
 
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Location

 

Commonwealth BuildingHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@inproceedings{Moser:2017:10.1109/ISCAS.2017.8050721,
author = {Moser, N and Rodriguez-Manzano, J and Yu, L-S and Kalofonou, M and de, Mateo S and Li, X and Sverre, Lande T and Toumazou, C and Georgiou, P},
doi = {10.1109/ISCAS.2017.8050721},
title = {Live Demonstration: A CMOS-Based ISFET Array for Rapid Diagnosis of the Zika Virus},
url = {http://dx.doi.org/10.1109/ISCAS.2017.8050721},
year = {2017}
}
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RIS format (EndNote, RefMan)

TY  - CPAPER
AB  - We demonstrate a diagnostics platform which integrates an ISFET array and a temperature control loop for isothermal DNA detection. The controller maintains a temperature of 63C to perform nucleic acid amplification which is detected by the on-chip sensors. The 32x32 ISFET array is first calibrated to cancel trapped charge and then measures the change in the pH of the reaction. The sensor data is sent to a microcontroller and the reaction is monitored in real-time using a MATLAB interface. Experiments confirm a change of 0.9 pH when tested for the presence of RNA associated with the Zika virus.
AU  - Moser,N
AU  - Rodriguez-Manzano,J
AU  - Yu,L-S
AU  - Kalofonou,M
AU  - de,Mateo S
AU  - Li,X
AU  - Sverre,Lande T
AU  - Toumazou,C
AU  - Georgiou,P
DO  - 10.1109/ISCAS.2017.8050721
PY  - 2017///
SN  - 2379-447X
TI  - Live Demonstration: A CMOS-Based ISFET Array for Rapid Diagnosis of the Zika Virus
UR  - http://dx.doi.org/10.1109/ISCAS.2017.8050721
ER  -
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