I am interested in how bacteria interact with plants. We use synthetic and systems biology approaches to better understand how molecular mechanisms impact on overall systems behaviour. Research activities span from molecular mechanisms that underpin bacterial system behaviour, to predictably alter their behaviour in plant environments. For example, we study the molecular program of Pseudomonas syringae that triggers plant pathogenicity and the regulation of nitrogen assimilation and fixation in a various bacteria. I am coordinating the systems and synthetic biology aspects of our strategic LoLa award to engineer nitrogen fixing bacteria to reduce our dependency on chemically produced nitrogen fertilisers (RCUK: BB/N003608/1).
et al., 2018, Mutualism between Klebsiella SGM 81 and Dianthus caryophyllus in modulating root plasticity and rhizospheric bacterial density, Plant and Soil, Vol:424, ISSN:0032-079X, Pages:273-288
et al., 2017, GlnK Facilitates the Dynamic Regulation of Bacterial Nitrogen AssimilationS, Biophysical Journal, Vol:112, ISSN:0006-3495, Pages:2219-2230
et al., 2017, Negative Autogenous Control of the Master Type III Secretion System Regulator HrpL in Pseudomonas syringae, Mbio, Vol:8, ISSN:2150-7511
et al., 2016, The NtrY-NtrX two-component system is involved in controlling nitrate assimilation in Herbaspirillum seropedicae strain SmR1, Febs Journal, Vol:283, ISSN:1742-464X, Pages:3919-3930
et al., 2015, In vitro and in vivo methodologies for studying the Sigma 54-dependent transcription., Methods Mol Biol, Vol:1276, Pages:53-79