Imperial College London
Alternate

MrJosephShalhoub

Faculty of Medicine, Department of Surgery & Cancer

Honorary Clinical Senior Lecturer
 
 
 
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Contact

 

j.shalhoub Website

 
 
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Location

 

Charing Cross HospitalCharing Cross Campus

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Summary

 

Publications

Citation

BibTex format

@article{Hartley:2021:10.3389/fcvm.2021.748137,
author = {Hartley, A and Shalhoub, J and Khamis, R},
doi = {10.3389/fcvm.2021.748137},
journal = {Frontiers in Cardiovascular Medicine},
pages = {1--9},
title = {Trends in mortality from aortic stenosis in Europe: 2000-2017},
url = {http://dx.doi.org/10.3389/fcvm.2021.748137},
volume = {8},
year = {2021}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - BackgroundTrends in mortality from aortic stenosis across European countries are not wellunderstood, especially given the significant growth in transcatheter aortic valveimplantation (TAVI) in the last 10 years.MethodsAge-standardised death rates were extracted from the World Health OrganisationMortality Database, using the International Classification of Diseases 10th editioncode for non-rheumatic aortic stenosis for those aged >45 years between 2000 and2017. The UK and countries from the European Union with at least 1,000,000inhabitants and at least 50% available datapoints over the study period were included:a total of 23 countries. Trends were described using Joinpoint regression analysis.ResultsNo reductions in mortality were demonstrated across all countries 2000-2017. Largeincreases in mortality were found for Croatia, Poland and Slovakia for both sexes(>300% change). Mortality plateaued in Germany from 2008 in females and 2012 inmales, whilst mortality in the Netherlands declined for both sexes from 2007. Mortalitydifferences between the sexes were observed, with greater mortality for males thanfemales across most countries.ConclusionsMortality from aortic stenosis has increased across Europe from 2000 to 2017. Thereare, however, sizable differences in mortality trends between Eastern and WesternEuropean countries. The need for health resource planning strategies to specificallytarget AS, particularly given the expected increase with aging populations, ishighlighted.
AU  - Hartley,A
AU  - Shalhoub,J
AU  - Khamis,R
DO  - 10.3389/fcvm.2021.748137
EP  - 9
PY  - 2021///
SN  - 2297-055X
SP  - 1
TI  - Trends in mortality from aortic stenosis in Europe: 2000-2017
T2  - Frontiers in Cardiovascular Medicine
UR  - http://dx.doi.org/10.3389/fcvm.2021.748137
UR  - https://www.frontiersin.org/articles/10.3389/fcvm.2021.748137/full
UR  - http://hdl.handle.net/10044/1/91742
VL  - 8
ER  -
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