Publications
3 results found
Statton BK, Smith J, Finnegan ME, et al., 2022, Temperature dependence, accuracy, and repeatability of T-1 and T-2 relaxation times for the ISMRM/NIST system phantom measured using MR fingerprinting, Magnetic Resonance in Medicine, Vol: 87, Pages: 1446-1460, ISSN: 0740-3194
PurposeBefore MR fingerprinting (MRF) can be adopted clinically, the derived quantitative values must be proven accurate and repeatable over a range of T1 and T2 values and temperatures. Correct assessment of accuracy and precision as well as comparison between measurements can only be performed when temperature is either controlled or corrected for. The purpose of this study was to investigate the temperature dependence of T1 and T2 MRF values and evaluate the accuracy and repeatability of temperature-corrected relaxation values derived from a B1-corrected MRF–fast imaging with steady-state precession implementation using 2 different dictionary sizes.MethodsThe International Society of MR in Medicine/National Institute of Standards and Technology phantom was scanned using an MRF sequence of 2 different lengths, a variable flip angle T1, and a multi-echo spin echo T2 at 14 temperatures ranging from 15°C to 28°C and investigated with a linear regression model. Temperature-corrected accuracy was evaluated by correlating T1 and T2 times from each MRF dictionary with reference values. Repeatability was assessed using the coefficient of variation, with measurements taken over 30 separate sessions.ResultsThere was a statistically significant fit of the model for MRF-derived T1 and T2 and temperature (p < 0.05) for all the spheres with a T1 > 500 ms. Both MRF methods showed a strong linear correlation with reference values for T1 (R2 = 0.996) and T2 (R2 = 0.982). MRF repeatability for T1 values was ≤1.4% and for T2 values was ≤3.4%.ConclusionMRF demonstrated relaxation times with a temperature dependence similar to that of conventional mapping methods. Temperature-corrected T1 and T2 values from both dictionaries showed adequate accuracy and excellent repeatability in this phantom study.
Mills M, Pelting V, Harris LM, et al., 2019, Comparison of MRI and neurosonogram 1-and 2-dimensional morphological measurements of the newborn corpus callosum, PEDIATRIC RESEARCH, Vol: 86, Pages: 355-359, ISSN: 0031-3998
Kousi E, Smith J, Ledger AE, et al., 2018, Quantitative evaluation of contrast agent uptake in standard fat-suppressed dynamic contrast-enhanced MRI examinations of the breast, MEDICAL PHYSICS, Vol: 45, Pages: 287-296, ISSN: 0094-2405
- Author Web Link
- Cite
- Citations: 6
This data is extracted from the Web of Science and reproduced under a licence from Thomson Reuters. You may not copy or re-distribute this data in whole or in part without the written consent of the Science business of Thomson Reuters.