Publications
137 results found
Marques R, Antunes I, Eksmond U, et al., 2008, B lymphocyte activation by coinfection prevents immune control of Friend virus infection, JOURNAL OF IMMUNOLOGY, Vol: 181, Pages: 3432-3440, ISSN: 0022-1767
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- Citations: 29
Yap MW, Lindemann D, Stanke N, et al., 2008, Restriction of foamy viruses by primate Trim5α, JOURNAL OF VIROLOGY, Vol: 82, Pages: 5429-5439, ISSN: 0022-538X
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- Citations: 55
Mortuza GB, Dodding MP, Goldstone DC, et al., 2008, Structure of B-MLV capsid amino-terminal domain reveals key features of viral tropism, Gag assembly and core formation, JOURNAL OF MOLECULAR BIOLOGY, Vol: 376, Pages: 1493-1508, ISSN: 0022-2836
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- Citations: 48
Stoye JP, Yap MW, 2008, Chance favors a prepared genome, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 105, Pages: 3177-3178, ISSN: 0027-8424
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- Citations: 17
Rajsbaum R, Stoye JP, O'Garra A, 2008, Type I interferon-dependent and -independent expression of tripartite motif proteins in immune cells, EUROPEAN JOURNAL OF IMMUNOLOGY, Vol: 38, Pages: 619-630, ISSN: 0014-2980
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- Citations: 127
Jern P, Stoye JP, Coffin JM, 2007, Role of APOBEC3 in genetic diversity among endogenous murine leukemia viruses, PLOS GENETICS, Vol: 3, Pages: 2014-2022, ISSN: 1553-7404
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- Citations: 102
Yap MW, Mortuza GB, Taylor IA, et al., 2007, The design of artificial retroviral restriction factors, VIROLOGY, Vol: 365, Pages: 302-314, ISSN: 0042-6822
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- Citations: 51
Campbell EM, Dodding MP, Yap MW, et al., 2007, TRIM5α cytoplasmic bodies are highly dynamic structures, MOLECULAR BIOLOGY OF THE CELL, Vol: 18, Pages: 2102-2111, ISSN: 1059-1524
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- Citations: 60
Ohkura S, Yap MW, Sheldon T, et al., 2006, All three variable regions of the TRIM5α B30.2 domain can contribute to the specificity of retrovirus restriction, JOURNAL OF VIROLOGY, Vol: 80, Pages: 8554-8565, ISSN: 0022-538X
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- Citations: 121
Bishop KN, Mortuza GB, Howell S, et al., 2006, Characterization of an amino-terminal dimerization domain from retroviral restriction factor Fv1, JOURNAL OF VIROLOGY, Vol: 80, Pages: 8225-8235, ISSN: 0022-538X
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- Citations: 15
Yap MW, Dodding MP, Stoye JP, 2006, Trim-cyclophilin A fusion proteins can restrict human immunodeficiency virus type 1 infection at two distinct phases in the viral life cycle, JOURNAL OF VIROLOGY, Vol: 80, Pages: 4061-4067, ISSN: 0022-538X
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- Citations: 68
Stoye JP, 2006, Koala retrovirus: a genome invasion in real time, GENOME BIOLOGY, Vol: 7, ISSN: 1474-760X
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- Citations: 48
Nisole S, Stoye JP, Saïb A, 2005, Trim family proteins:: Retroviral restriction and antiviral defence, NATURE REVIEWS MICROBIOLOGY, Vol: 3, Pages: 799-808, ISSN: 1740-1526
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- Citations: 599
Dodding MP, Bock M, Yap MW, et al., 2005, Capsid processing requirements for abrogation of Fv1 and Ref1 restriction, JOURNAL OF VIROLOGY, Vol: 79, Pages: 10571-10577, ISSN: 0022-538X
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- Citations: 44
Yap MW, Nisole S, Stoye JP, 2005, A single amino acid change in the SPRY domain of human Trim5α leads to HIV-1 restriction, CURRENT BIOLOGY, Vol: 15, Pages: 73-78, ISSN: 0960-9822
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- Citations: 332
Harrison I, Takeuchi Y, Bartosch B, et al., 2004, Determinants of high titer in recombinant porcine endogenous retroviruses, JOURNAL OF VIROLOGY, Vol: 78, Pages: 13871-13879, ISSN: 0022-538X
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- Citations: 89
Mortuza GB, Haire LF, Stevens A, et al., 2004, High-resolution structure of a retroviral capsid hexameric amino-terminal domain, NATURE, Vol: 431, Pages: 481-485, ISSN: 0028-0836
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- Citations: 161
Nisole S, Lynch C, Stoye JP, et al., 2004, A trim5-cyclophilin A fusion protein found in owl monkey kidney cells can restrict HIV-1, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 101, Pages: 13324-13328, ISSN: 0027-8424
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- Citations: 247
Stevens A, Bock M, Ellis S, et al., 2004, Retroviral capsid determinants of <i>Fv1</i> NB and NR tropism, JOURNAL OF VIROLOGY, Vol: 78, Pages: 9592-9598, ISSN: 0022-538X
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- Citations: 51
Yap MW, Nisole S, Lynch C, et al., 2004, Trim5α protein restricts both HIV-1 and murine leukemia virus, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 101, Pages: 10786-10791, ISSN: 0027-8424
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- Citations: 378
Taylor WR, Stoye JP, 2004, Consensus structural models for the amino terminal domain of the retrovirus restriction gene Fv1 and the murine leukaemia virus capsid proteins., BMC Struct Biol, Vol: 4
BACKGROUND: The mouse Fv1 (friend virus) susceptibility gene inhibits the development of the murine leukaemia virus (MLV) by interacting with its capsid (CA) protein. As no structures are available for these proteins we have constructed molecular models based on distant sequence similarity to other retroviral capsid proteins. RESULTS: Molecular models were constructed for the amino terminal domains of the probable capsid-like structure for the mouse Fv1 gene product and the capsid protein of the MLV. The models were based on sequence alignments with a variety of other retrovirus capsid proteins. As the sequence similarity of these proteins with MLV and especially Fv1 is very distant, a threading method was employed that incorporates predicted secondary structure and multiple sequence information. The resulting models were compared with equivalent models constructed using the sequences of the capsid proteins of known structure. CONCLUSIONS: These comparisons suggested that the MLV model should be accurate in the core but with significant uncertainty in the loop regions. The Fv1 model may have some additional errors in the core packing of its helices but the resulting model gave some support to the hypothesis that it adopts a capsid-like structure.
Yap MW, Stoye JP, 2003, Intracellular localisation of Fv1, VIROLOGY, Vol: 307, Pages: 76-89, ISSN: 0042-6822
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- Citations: 19
Yap MW, Stoye JP, 2003, Bending out and breaking away: host-cell accomplices in retroviral escape., J Biol, Vol: 3
Budding through the host-cell membrane is a key step in the life cycle of many viruses. Recent studies of retrovirus replication implicate a large number of cellular proteins in this process.
Stoye JP, 2002, An intracellular block to primate lentivirus replication, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 99, Pages: 11549-11551, ISSN: 0027-8424
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- Citations: 45
Stoye JP, 2001, Endogenous retroviruses: Still active after all these years?, CURRENT BIOLOGY, Vol: 11, Pages: R914-R916, ISSN: 0960-9822
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- Citations: 107
Bishop KN, Bock M, Towers G, et al., 2001, Identification of the regions of Fv1 necessary for murine leukemia virus restriction, JOURNAL OF VIROLOGY, Vol: 75, Pages: 5182-5188, ISSN: 0022-538X
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- Citations: 55
Patience C, Switzer WM, Takeuchi Y, et al., 2001, Multiple groups of novel retroviral genomes in pigs and related species, JOURNAL OF VIROLOGY, Vol: 75, Pages: 2771-2775, ISSN: 0022-538X
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- Citations: 173
Bock M, Stoye JP, 2000, Endogenous retroviruses and the human germline, CURRENT OPINION IN GENETICS & DEVELOPMENT, Vol: 10, Pages: 651-655, ISSN: 0959-437X
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- Citations: 95
Towers G, Bock M, Martin S, et al., 2000, A conserved mechanism of retrovirus restriction in mammals, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 97, Pages: 12295-12299, ISSN: 0027-8424
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- Citations: 208
Bock M, Bishop KN, Towers G, et al., 2000, Use of a transient assay for studying the genetic determinants of <i>Fv1</i> restriction, JOURNAL OF VIROLOGY, Vol: 74, Pages: 7422-7430, ISSN: 0022-538X
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- Citations: 120
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