Publications
137 results found
Stoye JP, Coffin JM, 2000, Reproductive biology - A provirus put to work, NATURE, Vol: 403, Pages: 715-+, ISSN: 0028-0836
- Author Web Link
- Cite
- Citations: 35
Stoye JP, 1999, The pathogenic potential of endogenous retroviruses: a sceptical view, TRENDS IN MICROBIOLOGY, Vol: 7, Pages: 430-430, ISSN: 0966-842X
- Author Web Link
- Cite
- Citations: 14
Cachón-González MB, San-José I, Cano A, et al., 1999, The <i>hairless</i> gene of the mouse:: Relationship of phenotypic effects with expression profile and genotype, DEVELOPMENTAL DYNAMICS, Vol: 216, Pages: 113-126, ISSN: 1058-8388
- Author Web Link
- Cite
- Citations: 50
Oliver PL, Stoye JP, 1999, Genetic analysis of <i>Gv1</i>, a gene controlling transcription of endogenous murine polytropic proviruses, JOURNAL OF VIROLOGY, Vol: 73, Pages: 8227-8234, ISSN: 0022-538X
- Author Web Link
- Cite
- Citations: 21
Begoña CachónGonzález M, SanJosé I, Cano A, et al., 1999, The hairless gene of the mouse: Relationship of phenotypic effects with expression profile and genotype, Developmental Dynamics, Vol: 216, Pages: 113-126, ISSN: 1058-8388
Takeuchi Y, Patience C, Magre S, et al., 1998, Host range and interference studies of three classes of pig endogenous retrovirus, JOURNAL OF VIROLOGY, Vol: 72, Pages: 9986-9991, ISSN: 0022-538X
- Author Web Link
- Cite
- Citations: 351
Stoye J, 1998, No clear answers on safety of pigs as tissue donor source, LANCET, Vol: 352, Pages: 666-667, ISSN: 0140-6736
- Author Web Link
- Cite
- Citations: 40
Stoye JP, 1998, Fv1, the mouse retrovirus resistance gene, REVUE SCIENTIFIQUE ET TECHNIQUE-OFFICE INTERNATIONAL DES EPIZOOTIES, Vol: 17, Pages: 269-277, ISSN: 0253-1933
- Author Web Link
- Cite
- Citations: 47
Stoye JP, Le Tissier P, Takeuchi Y, et al., 1998, Endogenous retroviruses: A potential problem for xenotransplantation?, XENOTRANSPLANTATION, Vol: 862, Pages: 67-74, ISSN: 0077-8923
- Author Web Link
- Cite
- Citations: 21
LeTissier P, Stoye JP, Takeuchi Y, et al., 1997, Two sets of human-tropic pig retrovirus, NATURE, Vol: 389, Pages: 681-682, ISSN: 0028-0836
- Author Web Link
- Cite
- Citations: 335
Best S, LeTissier PR, Stoye JP, 1997, Endogenous retroviruses and the evolution of resistance to retroviral infection, TRENDS IN MICROBIOLOGY, Vol: 5, Pages: 313-318, ISSN: 0966-842X
- Author Web Link
- Cite
- Citations: 71
Stoye JP, 1997, Xenotransplantation. Proviruses pose potential problems., Nature, Vol: 386, Pages: 126-127, ISSN: 0028-0836
Boeke JD, Stoye JP, 1997, Retrotransposons, Endogenous Retroviruses, and the Evolution of Retroelements
The retroelements are as diverse an assemblage of related molecular entities as can be found anywhere. With the exception of the retroviruses themselves, retroelements are genetic parasites that inhabit the genomes of all eukaryotes and many prokaryotes. The infectious retroviruses can be considered a highly evolved pinnacle on the complex phylogenetic tree that makes up the retroelements. The root of this tree is believed by many to be an ancient cellular reverse transcriptase gene, as originally proposed by Temin (1980), although this remains controversial. It is useful to consider the retroelements in comparison to the infectious retroviruses. The retroelement types, summarized in Table 1, include the endogenous retroviruses, the retrotransposons, the “retrotranscripts” (including the Alu-like sequences and the processed pseudogenes), and the prokaryotic retrons (also known as multicopy single-stranded DNAs [msDNAs]). Retroelements are known primarily as mobile DNA species integrated at various positions in the genomes of their host species, although most of them also have important extrachromosomal DNA forms. From the mitochondrial and chloroplast compartments of various organisms, the mobile group II introns (referred to here as retrointrons) and the retroplasmids are recognized as retroelements. Yet another major grouping of retroelements is the “pararetroviruses,” a group of true viruses with DNA genomes that, in a curious permutation of the retroviral life cycle, replicate via a cellular RNA intermediate but do not normally integrate into the host genome.
Best S, LeTissier P, Towers G, et al., 1996, Positional cloning of the mouse retrovirus restriction gene Fv1, NATURE, Vol: 382, Pages: 826-829, ISSN: 0028-0836
- Author Web Link
- Cite
- Citations: 382
Mock BA, Stoye J, Spence J, et al., 1996, Mouse Chromosome 4, MAMMALIAN GENOME, Vol: 6, Pages: S73-S96, ISSN: 0938-8990
- Author Web Link
- Cite
- Citations: 12
STOYE JP, COFFIN JM, 1995, THE DANGERS OF XENOTRANSPLANTATION, NATURE MEDICINE, Vol: 1, Pages: 1100-1100, ISSN: 1078-8956
- Author Web Link
- Cite
- Citations: 60
LUSH IE, HORNIGOLD N, KING P, et al., 1995, THE GENETICS OF TASTING IN MICE .7. GLYCINE REVISITED, AND THE CHROMOSOMAL LOCATION OF SAC AND SOA, GENETICAL RESEARCH, Vol: 66, Pages: 167-174, ISSN: 0016-6723
- Author Web Link
- Cite
- Citations: 88
STOYE JP, KAUSHIK N, JEREMIAH S, et al., 1995, GENETIC-MAP OF THE REGION SURROUNDING THE RETROVIRUS RESTRICTION LOCUS, FV1, ON MOUSE CHROMOSOME-4, MAMMALIAN GENOME, Vol: 6, Pages: 31-36, ISSN: 0938-8990
- Author Web Link
- Cite
- Citations: 12
KAUSHIK N, STOYE JP, 1994, INTRACISTERNAL A-TYPE PARTICLE ELEMENTS AS GENETIC-MARKERS - DETECTION BY REPEAT ELEMENT VIRAL ELEMENT AMPLIFIED LOCUS-PCR, MAMMALIAN GENOME, Vol: 5, Pages: 688-695, ISSN: 0938-8990
- Author Web Link
- Cite
- Citations: 7
CACHONGONZALEZ MB, FENNER S, COFFIN JM, et al., 1994, STRUCTURE AND EXPRESSION OF THE HAIRLESS GENE OF MICE, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 91, Pages: 7717-7721, ISSN: 0027-8424
- Author Web Link
- Cite
- Citations: 151
RINCHIK EM, STOYE JP, FRANKEL WN, et al., 1993, MOLECULAR ANALYSIS OF VIABLE SPONTANEOUS AND RADIATION-INDUCED ALBINO (C)-LOCUS MUTATIONS IN THE MOUSE, MUTATION RESEARCH, Vol: 286, Pages: 199-207, ISSN: 0921-8262
- Author Web Link
- Cite
- Citations: 37
GROOT PC, MOEN CJA, DIETRICH W, et al., 1992, THE RECOMBINANT CONGENIC STRAINS FOR ANALYSIS OF MULTIGENIC TRAITS - GENETIC COMPOSITION, FASEB JOURNAL, Vol: 6, Pages: 2826-2835, ISSN: 0892-6638
- Author Web Link
- Cite
- Citations: 76
FRANKEL WN, LEE BK, STOYE JP, et al., 1992, CHARACTERIZATION OF THE ENDOGENOUS NONECOTROPIC MURINE LEUKEMIA VIRUSES OF NZB/B1NJ AND SM/J INBRED STRAINS, MAMMALIAN GENOME, Vol: 2, Pages: 110-122, ISSN: 0938-8990
- Author Web Link
- Cite
- Citations: 51
ABBOTT CM, BLANK R, EPPIG JT, et al., 1992, MOUSE CHROMOSOME-4, MAMMALIAN GENOME, Vol: 3, Pages: S55-S64, ISSN: 0938-8990
- Author Web Link
- Cite
- Citations: 29
STOYE JP, MORONI C, COFFIN JM, 1991, VIROLOGICAL EVENTS LEADING TO SPONTANEOUS AKR THYMOMAS, JOURNAL OF VIROLOGY, Vol: 65, Pages: 1273-1285, ISSN: 0022-538X
- Author Web Link
- Cite
- Citations: 154
, 1990, A Linkage Map of Endogenous Murine Leukemia Proviruses, Genetics, Vol: 125, Pages: 455-455, ISSN: 0016-6731
FRANKEL WN, STOYE JP, TAYLOR BA, et al., 1990, A LINKAGE MAP OF ENDOGENOUS MURINE LEUKEMIA PROVIRUSES, GENETICS, Vol: 124, Pages: 221-236, ISSN: 0016-6731
- Author Web Link
- Cite
- Citations: 197
FRANKEL WN, STOYE JP, TAYLOR BA, et al., 1989, GENETIC IDENTIFICATION OF ENDOGENOUS POLYTROPIC PROVIRUSES BY USING RECOMBINANT INBRED MICE, JOURNAL OF VIROLOGY, Vol: 63, Pages: 3810-3821, ISSN: 0022-538X
- Author Web Link
- Cite
- Citations: 128
FRANKEL WN, STOYE JP, TAYLOR BA, et al., 1989, GENETIC-ANALYSIS OF ENDOGENOUS XENOTROPIC MURINE LEUKEMIA VIRUSES - ASSOCIATION WITH 2 COMMON-MOUSE MUTATIONS AND THE VIRAL RESTRICTION LOCUS FV-1, JOURNAL OF VIROLOGY, Vol: 63, Pages: 1763-1774, ISSN: 0022-538X
- Author Web Link
- Cite
- Citations: 135
Coffin JM, Stoye JP, Frankel WN, 1989, Genetics of endogenous murine leukemia viruses., Ann N Y Acad Sci, Vol: 567, Pages: 39-49, ISSN: 0077-8923
Inbred strains of mice contain in the genome 40-60 endogenous proviruses related to murine leukemia virus. To assess the genetic and pathogenic consequences of these to the host, we have developed a strategy to distinguish among the three different host-range subgroups--xenotropic, polytropic and modified polytropic--by using oligonucleotide probes specific for a polymorphic region in env. Each of these proteins detects a relatively small number of bands in a Southern blot, thus permitting us to enumerate all individual proviruses of this group. Using this approach, we have determined the distribution of different proviruses among inbred and recombinant inbred (RI) strains congenic or coisogenic for specific mutants. Using the RI results, we have been able to place over 100 proviruses on the mouse genetic map. A number of these are closely linked to well-characterized mutations, and we have been able to establish that at least one mutation, hr (hairless), was caused by a proviral insertion. If the other close linkages also prove to reflect causality, we estimate that up to 5% of recessive mutations in the mouse might be caused by insertion of proviruses of this group. Using a similar probe strategy, we have followed the evolution of murine leukemia viruses during spontaneous leukemogenesis in AKR mice. We have found that the final leukemogenic (MCF) virus is a recombinant of three different endogenous parents; an ecotropic virus, a polytropic virus that directs the gp70 region of env, and a xenotropic virus (identified as the inducible element Bxv-1) that directs the LTR. In addition to the recombinations, all such viruses also have a reduplication of the enhancer region of the LTR, compared to the endogenous parent. MCF viruses are created by these three genetic changes, which occur in a reproducible fashion and appear in the thymus between 10 and 14 weeks of age.
This data is extracted from the Web of Science and reproduced under a licence from Thomson Reuters. You may not copy or re-distribute this data in whole or in part without the written consent of the Science business of Thomson Reuters.