Imperial College London

Dr Jose V. Torres Pérez

Faculty of MedicineDepartment of Brain Sciences

Research Associate in Epigenetics - UK Dementia Research Ins
 
 
 
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Contact

 

j.torres-perez

 
 
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Location

 

Building E - Sir Michael UrenWhite City Campus

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Summary

 

Summary

Dr Torres-Pérez is a neurobiologist interested on the epigenetic landscape regulating neural development and its impact on neurodegenerative disorders. He has been successfully involved in a wide range of multi-disciplinary projects spanning from clinical settings to academic scenarios with engineers/materials scientists and experimental psychologists.

After gaining his undergraduate degree in Biology at the University of Valencia, he moved to Oxford for a 6-month internship at the Wellcome Trust Centre for Human Genetics. After that, Dr Torres-Pérez did a MRes in Neuroscience at the Autonomous University of Barcelona. For his PhD in Clinical Medicine Research, he worked with Dr Istvan Nagy at the Chelsea and Westminster Hospital, Imperial College London, where he investigated the role different epigenetic tags, mainly histone post-translational modifications, play on the transition from acute to chronic pain at neurons and glial cells of both spinal cord and dorsal root ganglia.

Dr Torres-Pérez has held two previous postdoctoral positions at Queen Mary University of London.  First at the School of Engineering and Materials Science, where he was performing high-resolution electrophysiology of primary cilia and single cell calcium recordings. Secondly, at the School of Biological and Chemical Sciences, where he used zebrafish as a reverse genetic model for comparative cognition by generating loss-of-function zebrafish lines using the CRISPR/Cas9 technology, performing differential gene expression analysis, and conducting behavioural analysis.

Publications

Journals

Ponzoni L, Melzi G, Marabini L, et al., 2021, Conservation of mechanisms regulating emotional-like responses on spontaneous nicotine withdrawal in zebrafish and mammals., Prog Neuropsychopharmacol Biol Psychiatry, Vol:111

Nagy I, Torres Perez J, Irfan J, et al., 2021, Histone post-translational modification as potential therapeutic targets for pain management, Trends in Pharmacological Sciences, ISSN:0165-6147

Evans JR, Torres-Perez JV, Miletto Petrazzini ME, et al., 2021, Stress reactivity elicits a tissue-specific reduction in telomere length in aging zebrafish (Danio rerio), Scientific Reports, Vol:11, ISSN:2045-2322

Ponzoni L, Teh M-T, Torres-Perez JV, et al., 2020, Increased Response to 3,4-Methylenedioxymethamphetamine (MDMA) Reward and Altered Gene Expression in Zebrafish During Short- and Long-Term Nicotine Withdrawal, Molecular Neurobiology, Vol:58, ISSN:0893-7648, Pages:1650-1663

Conference

Torres-Perez JV, Brennan CH, 2021, Restoring Wnt/beta-catenin pathway as potential therapeutics for Williams syndrome-associated anxiety disorders, 2000 Meeting of the British-Pharmacological-Society (PHARMACOLOGY), WILEY, Pages:447-448, ISSN:0007-1188

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