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@article{Sita-Lumsden:2013:10.1038/bjc.2013.192,
author = {Sita-Lumsden, A and Dart, DA and Waxman, J and Bevan, CL},
doi = {10.1038/bjc.2013.192},
journal = {British Journal of Cancer},
pages = {1925--1930},
title = {Circulating microRNAs as potential new biomarkers for prostate cancer},
url = {http://dx.doi.org/10.1038/bjc.2013.192},
volume = {108},
year = {2013}
}

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TY  - JOUR
AB  - Since they were first described in the 1990s, circulating microRNAs (miRNAs) have provided an active and rapidly evolving area of current research that has the potential to transform cancer diagnostics and therapeutics. In particular, miRNAs could provide potential new biomarkers for prostate cancer, the most common cause of cancer in UK men. Current diagnostic tests for prostate cancer have low specificity and poor sensitivity. Further, although many prostate cancers are so slow growing as not to pose a major risk to health, there is currently no test to distinguish between these and cancers that will become aggressive and life threatening. Circulating miRNAs are highly stable and are both detectable and quantifiable in a range of accessible bio fluids, thus have the potential to be useful diagnostic, prognostic and predictive biomarkers. This review aims to summarise the current understanding of circulating miRNAs in prostate cancer patients and their potential role as biomarkers.
AU  - Sita-Lumsden,A
AU  - Dart,DA
AU  - Waxman,J
AU  - Bevan,CL
DO  - 10.1038/bjc.2013.192
EP  - 1930
PY  - 2013///
SN  - 1532-1827
SP  - 1925
TI  - Circulating microRNAs as potential new biomarkers for prostate cancer
T2  - British Journal of Cancer
UR  - http://dx.doi.org/10.1038/bjc.2013.192
UR  - http://hdl.handle.net/10044/1/37563
VL  - 108
ER  -

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