Imperial College London
Alternate

ProfessorWisiaWedzicha

Faculty of Medicine, National Heart & Lung Institute

Consul (clinical) for the Faculty of Medicine
 
 
 
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Contact

 

j.wedzicha

 
 
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Location

 

B142Guy Scadding BuildingRoyal Brompton Campus

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Summary

 

Publications

Citation

BibTex format

@article{Long:2020:10.1186/s12931-020-1279-4,
author = {Long, GH and Southworth, T and Kolsum, U and Donaldson, GC and Wedzicha, JA and Brightling, CE and Singh, D},
doi = {10.1186/s12931-020-1279-4},
journal = {Respiratory Research},
title = {The stability of blood Eosinophils in chronic obstructive pulmonary disease},
url = {http://dx.doi.org/10.1186/s12931-020-1279-4},
volume = {21},
year = {2020}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Blood eosinophils are a predictive biomarker of inhaled corticosteroid response in chronic obstructive pulmonary disease (COPD). We investigated blood eosinophil stability over 1 year using the Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2019 thresholds of < 100, 100- < 300 and ≥ 300 eosinophils/μL in 225 patients from the COPDMAP cohort. Blood eosinophils showed good stability (rho: 0.71, p < 0.001, ICC 0.84), and 69.3% of patients remained in the same eosinophil category at 1 year. 85.3% of patients with eosinophils < 100 cells/μL had stable counts. The majority of blood eosinophil counts remain stable over 1 year using the GOLD 2019 thresholds.
AU  - Long,GH
AU  - Southworth,T
AU  - Kolsum,U
AU  - Donaldson,GC
AU  - Wedzicha,JA
AU  - Brightling,CE
AU  - Singh,D
DO  - 10.1186/s12931-020-1279-4
PY  - 2020///
SN  - 1465-9921
TI  - The stability of blood Eosinophils in chronic obstructive pulmonary disease
T2  - Respiratory Research
UR  - http://dx.doi.org/10.1186/s12931-020-1279-4
UR  - https://www.ncbi.nlm.nih.gov/pubmed/31924207
UR  - http://hdl.handle.net/10044/1/76829
VL  - 21
ER  -
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