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BibTex format

@article{Perry:2020:10.1039/d0cc00196a,
author = {Perry, H and Botnar, R and Wilton-Ely, J},
doi = {10.1039/d0cc00196a},
journal = {Chemical Communications},
pages = {4037--4046},
title = {Gold nanomaterials functionalised with gadolinium chelates and their application in multimodal imaging and therapy},
url = {http://dx.doi.org/10.1039/d0cc00196a},
volume = {56},
year = {2020}
}

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TY  - JOUR
AB  - Over the last decade, much work has been dedicated to improving the performance of gadolinium-based magnetic resonance imaging (MRI) contrast agents by tethering them to biocompatible gold nanoparticles. The enhancement in performance (measured in terms of ‘relaxivity’) stems from the restriction in motion experienced by the gadolinium chelates on being attached to the gold nanoparticle surface. More recently, the unique properties of gold nanoparticles have been exploited to create very promising tools for multimodal imaging and MRI-guided therapies. This review addresses the progress made in the design of gadolinium-functionalised gold nanoparticles for use in MRI, multimodal imaging and theranostics. It also seeks to connect the chemical properties of these assemblies with potential application in the clinic.
AU  - Perry,H
AU  - Botnar,R
AU  - Wilton-Ely,J
DO  - 10.1039/d0cc00196a
EP  - 4046
PY  - 2020///
SN  - 1359-7345
SP  - 4037
TI  - Gold nanomaterials functionalised with gadolinium chelates and their application in multimodal imaging and therapy
T2  - Chemical Communications
UR  - http://dx.doi.org/10.1039/d0cc00196a
UR  - https://pubs.rsc.org/en/Content/ArticleLanding/2020/CC/D0CC00196A#!divAbstract
UR  - http://hdl.handle.net/10044/1/77618
VL  - 56
ER  -

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Professor James Wilton-Ely

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