Imperial College London

Professor James Wilton-Ely

Faculty of Natural SciencesDepartment of Chemistry

Professor of Inorganic Chemistry
 
 
 
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Contact

 

+44 (0)20 7594 9718j.wilton-ely Website

 
 
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Location

 

601bMolecular Sciences Research HubWhite City Campus

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Summary

 

Publications

Citation

BibTex format

@article{Shi:2021:10.7150/ntno.56432,
author = {Shi, X and Perry, H and Wilton-Ely, J},
doi = {10.7150/ntno.56432},
journal = {Nanotheranostics},
pages = {155--165},
title = {Strategies for the functionalisation of gold nanorods to reduce toxicity and aid clinical translation},
url = {http://dx.doi.org/10.7150/ntno.56432},
volume = {5},
year = {2021}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - Gold nanorods (GNRs) show great promise as photothermal therapy agents due to their remarkable ability to convert light into heat. In most cases, gold nanorods are synthesised via a seed-mediated method assisted by surfactants. However, the toxicity of these surfactants, principally cetrimonium ions, has prevented GNRs from being used more widely in vivo. To address this issue, various detoxification and functionalisation approaches have been proposed in recent years to replace or cover surfactant coatings on the gold surface. In this short review, the advantages and limitations of each approach are examined in the context of the recent progress made towards the design of GNRs suitable for use in the body.
AU - Shi,X
AU - Perry,H
AU - Wilton-Ely,J
DO - 10.7150/ntno.56432
EP - 165
PY - 2021///
SN - 2206-7418
SP - 155
TI - Strategies for the functionalisation of gold nanorods to reduce toxicity and aid clinical translation
T2 - Nanotheranostics
UR - http://dx.doi.org/10.7150/ntno.56432
UR - https://www.ntno.org/v05p0155.htm
UR - http://hdl.handle.net/10044/1/86395
VL - 5
ER -