Imperial College London
Portrait Picture

Professor Jake Baum

Faculty of Natural Sciences, Department of Life Sciences

Visiting Professor
 
 
 
//

Contact

 

+44 (0)20 7594 5420jake.baum Website

 
 
//

Location

 

c/o Baum labSir Alexander Fleming BuildingSouth Kensington Campus

//

Summary

 

Publications

Citation

BibTex format

@article{Tardieux:2016:10.1083/jcb.201605100,
author = {Tardieux, I and Baum, J},
doi = {10.1083/jcb.201605100},
journal = {Journal of Cell Biology},
pages = {507--515},
title = {Reassessing the mechanics of parasite motility and host-cell invasion},
url = {http://dx.doi.org/10.1083/jcb.201605100},
volume = {214},
year = {2016}
}
Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - The capacity to migrate is fundamental to multicellular and single-celled life. Apicomplexan parasites, an ancient protozoan clade that includes malaria parasites (Plasmodium) and Toxoplasma, achieve remarkable speeds of directional cell movement. This rapidity is achieved via a divergent actomyosin motor system, housed within a narrow compartment that lies underneath the length of the parasite plasma membrane. How this motor functions at a mechanistic level during motility and host cell invasion is a matter of debate. Here, we integrate old and new insights toward refining the current model for the function of this motor with the aim of revitalizing interest in the mechanics of how these deadly pathogens move.
AU  - Tardieux,I
AU  - Baum,J
DO  - 10.1083/jcb.201605100
EP  - 515
PY  - 2016///
SN  - 1540-8140
SP  - 507
TI  - Reassessing the mechanics of parasite motility and host-cell invasion
T2  - Journal of Cell Biology
UR  - http://dx.doi.org/10.1083/jcb.201605100
UR  - http://hdl.handle.net/10044/1/39704
VL  - 214
ER  -
Download