Imperial College London
Portrait Picture

DrJamesMoss

Faculty of Medicine, National Heart & Lung Institute

Principal Teaching Fellow
 
 
 
//

Contact

 

james.moss

 
 
//

Location

 

G02 Faculty Education OfficeSir Alexander Fleming BuildingSouth Kensington Campus

//

Summary

 

Publications

Citation

BibTex format

@article{Moss:2014:2014/102164,
author = {Moss, J and Tew, GA and Copeland, RJ and Stout, M and Billings, CG and Saxton, JM and Winter, EM and Bianchi, SM},
doi = {2014/102164},
journal = {BioMed Research International},
pages = {1--8},
title = {Effects of a Pragmatic Lifestyle Intervention for Reducing Body Mass in Obese Adults with Obstructive Sleep Apnoea: A Randomised Controlled Trial},
url = {http://dx.doi.org/10.1155/2014/102164},
volume = {2014},
year = {2014}
}
Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - <jats:p>This study investigated the effects of a pragmatic lifestyle intervention in obese adults with continuous positive airway pressure-treated obstructive sleep apnoea hypopnoea syndrome (OSAHS). Sixty patients were randomised 1 : 1 to either a 12-week lifestyle intervention or an advice-only control group. The intervention involved supervised exercise sessions, dietary advice, and the promotion of lifestyle behaviour change using cognitive-behavioural techniques. Outcomes were assessed at baseline (week 0), intervention end-point (week 13), and follow-up (week 26). The primary outcome was 13-week change in body mass. Secondary outcomes included anthropometry, blood-borne biomarkers, exercise capacity, and health-related quality of life. At end-point, the intervention group exhibited small reductions in body mass (−1.8 [−3.0, −0.5] kg;<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mi>P</mml:mi><mml:mo>=</mml:mo><mml:mn>0.007</mml:mn></mml:math>) and body fat percentage (−1 [−2, 0]%;<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M2"><mml:mi>P</mml:mi><mml:mo>=</mml:mo><mml:mn>0.044</mml:mn></mml:math>) and moderate improvements in C-reactive protein (−1.3 [−2.4, −0.2] mg·L<jats:sup>−1</jats:sup>;<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M3"><mml:mi>P</mml:mi><mml:mo>=</mml:mo><mml:mn>0.028</mml:mn></mml:math>) and exercise capacity (95 [50, 139] m;<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M4"><mml:mi>P</mml:mi><mml:mo><</mml:mo><mml:mn>0.001</mml:mn></mml:math>). At follow-up, changes in body mass (&minu
AU  - Moss,J
AU  - Tew,GA
AU  - Copeland,RJ
AU  - Stout,M
AU  - Billings,CG
AU  - Saxton,JM
AU  - Winter,EM
AU  - Bianchi,SM
DO  - 2014/102164
EP  - 8
PY  - 2014///
SN  - 2314-6133
SP  - 1
TI  - Effects of a Pragmatic Lifestyle Intervention for Reducing Body Mass in Obese Adults with Obstructive Sleep Apnoea: A Randomised Controlled Trial
T2  - BioMed Research International
UR  - http://dx.doi.org/10.1155/2014/102164
VL  - 2014
ER  -
Download