Imperial College London

Dr James A Seddon

Faculty of MedicineDepartment of Infectious Disease

Clinical Senior Lecturer in Paediatric Infectious Disease



+44 (0)20 7594 3179james.seddon




235Norfolk PlaceSt Mary's Campus





I am a Clinical Senior Lecturer at Imperial, an Honorary Consultant in Paediatric Infectious Diseases and a Honorary Associate Professor at Stellenbosch University. I divide my time between Cape Town and London. Clinical work takes place at St. Mary's Hospital in London where I look after children with complex infectious diseases. My major area of research is that of children with tuberculosis, specifically drug-resistant forms.

I studied medicine at Corpus Christi College, Cambridge and Imperial College London and have carried out paediatric training in both the UK and Australia. Before clinical academia, I was an infantry officer in the British army, worked as a doctor for Médecins Sans Frontières in Côte d'Ivoire and spent time on an expedition in Patagonia. I undertook my PhD in Cape Town, studying drug-resistant tuberculosis in children, and have gained Diplomas in Tropical Medicine and Paediatric Infectious Diseases. During 2017 I spent six months at the Department of Global Health and Social Medicine in Harvard University on a Fulbright Scholarship evaluating different strategies to combat drug-resistant tuberculosis in children.

I am currently funded through an MRC Clinician Scientist Fellowship to evaluate correlates of risk in children exposed to multidrug-resistant tuberculosis.

Selected Publications

Journal Articles

Ganmaa D, Uyanga B, Zhou X, et al., 2020, Vitamin D supplements and prevention of tuberculosis infection and disease, New England Journal of Medicine, Vol:383, ISSN:0028-4793, Pages:359-368

Yuen C, Seddon J, Keshavjee S, et al., 2020, Risk-benefit analysis of tuberculosis infection testing for household contact management in high-burden countries: a mathematical modelling study, The Lancet Global Health, Vol:8, ISSN:2214-109X, Pages:e672-e680

Snow KJ, Cruz AT, Seddon JA, et al., 2020, Adolescent tuberculosis, The Lancet Child & Adolescent Health, Vol:4, ISSN:2352-4642, Pages:68-79

Reid MJA, Arinaminpathy N, Bloom A, et al., 2019, Building a tuberculosis-free world: The Lancet Commission on tuberculosis, The Lancet, Vol:393, ISSN:0140-6736, Pages:1331-1384

Dodd P, Yuen C, Becerra M, et al., 2018, The potential impact of household contact management on childhood tuberculosis: a mathematical modelling study, The Lancet Global Health, Vol:6, ISSN:2214-109X, Pages:e1329-e1338

Dodd P, Yuen C, Sismanidis C, et al., 2017, The global burden of tuberculosis mortality in children: amathematical modelling study, Lancet Global Health, Vol:5, ISSN:2214-109X, Pages:e898-e906

Dodd P, Sismanidis C, Seddon JA, 2016, The global burden of drug-resistant tuberculosis in children: a mathematical model, Lancet Infectious Diseases, Vol:16, ISSN:1473-3099, Pages:1193-1201

Dodd PJ, Gardiner E, Coghlan R, et al., 2014, Burden of childhood tuberculosis in 22 high-burden countries: a mathematical modelling study, The Lancet Global Health, Vol:2, ISSN:2214-109X, Pages:e453-e459

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