Imperial College London
Alternate

Jeff Imai-Eaton

Faculty of Medicine, School of Public Health

Senior Research Fellow
 
 
 
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Contact

 

jeffrey.eaton

 
 
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Location

 

UG7Norfolk PlaceSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Nsanzimana:2022:10.1016/j.ijid.2022.01.032,
author = {Nsanzimana, S and Rwibasira, G and Malamba, SS and Musengimana, G and Kayirangwa, E and Jonnalagadda, S and Fazito, E and Eaton, J and Mugisha, V and Remera, E and Semakula, M and Mulindabigwi, A and Omolo, FJ and Wiesner, L and Moore, C and Patel, H and Justman, J},
doi = {10.1016/j.ijid.2022.01.032},
journal = {International Journal of Infectious Diseases},
pages = {245--254},
title = {HIV incidence and prevalence among adults aged 15-64 years in Rwanda: Results from the Rwanda Population-based HIV Impact Assessment (RPHIA) and District-level Modeling, 2019},
url = {http://dx.doi.org/10.1016/j.ijid.2022.01.032},
volume = {116},
year = {2022}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - ObjectivesThe 2018–19 Rwanda Population-based HIV Impact Assessment (RPHIA) was conducted to measure national HIV incidence and prevalence. District-level estimates were modeled to inform resources allocation.MethodsRPHIA was a nationally representative cross-sectional household survey. Consenting adults were interviewed and tested for HIV using the national diagnostic algorithm followed by laboratory-based confirmation of HIV status, and testing for viral load (VL), limiting antigen (LAg) avidity and presence of antiretrovirals. Incidence was calculated using normalized optical density ≤ 1•5, VL ≥ 1,000 copies/mL, and undetectable antiretrovirals. Survey and programmatic data were used to model district-level HIV incidence and prevalence.ResultsOf 31,028 eligible adults, 98•7% participated in RPHIA and 934 tested HIV positive. HIV prevalence among adults in Rwanda was 3•0% (95% CI:2•7–3•3). National HIV incidence was 0•08% (95% CI:0•02–0•14) and 0•11% (95% CI:0•00–0•26) in the City of Kigali (CoK). Based on district-level modeling, HIV incidence was greatest in the three CoK districts (0•11% to 0•15%) and varied across other districts (0•03% to 0•10%).ConclusionsHIV prevalence among adults in Rwanda is 3.0%; HIV incidence is low at 0.08%. District-level modeling has identified disproportionately affected urban hotspots: areas to focus resources.
AU  - Nsanzimana,S
AU  - Rwibasira,G
AU  - Malamba,SS
AU  - Musengimana,G
AU  - Kayirangwa,E
AU  - Jonnalagadda,S
AU  - Fazito,E
AU  - Eaton,J
AU  - Mugisha,V
AU  - Remera,E
AU  - Semakula,M
AU  - Mulindabigwi,A
AU  - Omolo,FJ
AU  - Wiesner,L
AU  - Moore,C
AU  - Patel,H
AU  - Justman,J
DO  - 10.1016/j.ijid.2022.01.032
EP  - 254
PY  - 2022///
SN  - 1201-9712
SP  - 245
TI  - HIV incidence and prevalence among adults aged 15-64 years in Rwanda: Results from the Rwanda Population-based HIV Impact Assessment (RPHIA) and District-level Modeling, 2019
T2  - International Journal of Infectious Diseases
UR  - http://dx.doi.org/10.1016/j.ijid.2022.01.032
UR  - https://www.sciencedirect.com/science/article/pii/S1201971222000315?via%3Dihub
UR  - http://hdl.handle.net/10044/1/93840
VL  - 116
ER  -
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