Summary
Our world is more interconnected than ever before. It stands to reason, then, that our health is connected to our food, the changing climate and our environment (animals, the places we go). In the Rhodes Lab we use a One Health approach to balance and optimise the health of humans, animals and the environment.
Within the Rhodes Lab we focus on:
- Developing laboratory methods, computational pipelines and surveillance tools for emerging fungal pathogens.
- Carrying out environmental sampling of air, soil and waterways to discover niches of fungal diversity and novel drug resistance mechanisms. By matching with clinical sampling, we can investigate the environmental-to-human transmission of pathogenic fungi.
- The impact of climate change as drivers of resistance and genetic diversity, using the human fungal pathogen Aspergillus fumigatus as a model organism.
Publications
Journals
Hui ST, Gifford H, Rhodes J, 2024, Emerging Antifungal Resistance in Fungal Pathogens, Current Clinical Microbiology Reports
Gangneux J-P, Rhodes JL, Papon N, 2023, Airway microbiome: environmental exposure-respiratory health nexus., Trends Mol Med, Vol:29, Pages:875-877
Simmons BC, Rhodes J, Rogers TR, et al., 2023, Genomic epidemiology identifies azole resistance due to TR₃₄/L98H in European Aspergillus fumigatus causing COVID-19-associated pulmonary aspergillosis, Journal of Fungi, Vol:9, ISSN:2309-608X, Pages:1104-1104
Auxier B, Debets AJM, Stanford FA, et al., 2023, The human fungal pathogen Aspergillus fumigatus can produce the highest known number of meiotic crossovers, Plos Biology, Vol:21, ISSN:1544-9173, Pages:1-17
Hemmings SJ, Rhodes JL, Fisher MC, 2023, Long-read Sequencing and de novo Genome Assembly of Three <i>Aspergillus fumigatus</i> Genomes, Mycopathologia, Vol:188, ISSN:0301-486X, Pages:409-412