Publications
188 results found
Hong J, Lee Y, Chansin GAT, et al., 2008, Design of a solid-state nanopore-based platform for single-molecule spectroscopy, NANOTECHNOLOGY, Vol: 19, ISSN: 0957-4484
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- Citations: 29
Srisa-Art M, Edel JB, 2008, Single molecule detection and isola-tion using droplet microfluidics, Pages: 140-142
We present a droplet microfluidic system integrated with optical detection to demonstrate high throughput detection and confinement of single molecule events. © 2008 CBMS.
Niu X, Edel JB, 2008, Geometrically mediated droplet merging in microchannels, Pages: 1423-1425
We present a novel method for controllably merging aqueous microdroplets within segmented flow microfluidic devices. Such geometrically mediated droplet merging involves simple fabrication procedures and is extremely robust in operation. Passive droplet merging of this type is likely to find application, in multistep ana-lytical procedures at high-throughput.
Niu X, Gulati S, Edel JB, et al., 2008, Pillar-induced droplet merging in microfluidic circuits, LAB ON A CHIP, Vol: 8, Pages: 1837-1841, ISSN: 1473-0197
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- Citations: 289
Cheong KH, Yi DK, Lee J-G, et al., 2008, Gold nanoparticles for one step DNA extraction and real-time PCR of pathogens in a single chamber, LAB ON A CHIP, Vol: 8, Pages: 810-813, ISSN: 1473-0197
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- Citations: 69
Srisa-Art M, deMello AJ, Edel JB, 2007, High-throughput DNA droplet assays using picoliter reactor volumes, ANALYTICAL CHEMISTRY, Vol: 79, Pages: 6682-6689, ISSN: 0003-2700
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- Citations: 126
Meller A, Atas E, Sutin J, et al., 2007, PHYS 3-Accurate single molecule FRET efficiency determination for surface immobilized DNA using maximum likelihood calculated lifetimes, ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol: 234, ISSN: 0065-7727
Chansin GAT, Hong J, Mulero R, et al., 2007, Single Molecule Spectroscopy Using Nanoporous Membranes, Nano Letters
de Mello AJ, Edel JB, 2007, Hydrodynamic focusing in microstructures: Improved detection efficiencies in subfemtoliter probe volumes, Publisher: AMER INST PHYSICS, ISSN: 0021-8979
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- Citations: 27
Edel JB, Eid JS, Meller A, 2007, Accurate single molecule FRET efficiency determination for surface immobilized DNA using maximum likelihood calculated lifetimes, JOURNAL OF PHYSICAL CHEMISTRY B, Vol: 111, Pages: 2986-2990, ISSN: 1520-6106
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- Citations: 27
Edel JB, Lahoud P, Cass AEG, et al., 2007, Discrimination between single <i>Escherichia coli</i> cells using time-resolved confocal spectroscopy, JOURNAL OF PHYSICAL CHEMISTRY B, Vol: 111, Pages: 1129-1134, ISSN: 1520-6106
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- Citations: 4
Edel JB, deMello AJ, 2007, Interphoton burst recurrence times: Single cell analysis in freely flowing solutions, APPLIED PHYSICS LETTERS, Vol: 90, ISSN: 0003-6951
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- Citations: 7
Huebner A, Srisa-Art M, Holt D, et al., 2007, Quantitative detection of protein expression in single cells using droplet microfluidics, CHEMICAL COMMUNICATIONS, Pages: 1218-1220, ISSN: 1359-7345
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- Citations: 311
Liu HQ, Edel JB, Bellan LM, et al., 2006, Electrospun polymer nanofibers as subwavelength optical waveguides incorporating quantum dots, SMALL, Vol: 2, Pages: 495-499, ISSN: 1613-6810
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- Citations: 139
Stavis SM, Edel JB, Li YG, et al., 2005, Single-molecule mobility and spectral measurements in submicrometer fluidic channels, JOURNAL OF APPLIED PHYSICS, Vol: 98, ISSN: 0021-8979
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- Citations: 20
Stavis SM, Edel JB, Li YG, et al., 2005, Detection and identification of nucleic acid engineered fluorescent labels in submicrometre fluidic channels, 4th Topical Conference on Nanoscale Science and Engineering of the American-Institute-of-Chemical-Engineers, Publisher: IOP PUBLISHING LTD, Pages: S314-S323, ISSN: 0957-4484
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- Citations: 30
Moran-Mirabal JM, Edel JB, Meyer GD, et al., 2005, Micrometer-sized supported lipid bilayer arrays for bacterial toxin binding studies through total internal reflection fluorescence microscopy, BIOPHYSICAL JOURNAL, Vol: 89, Pages: 296-305, ISSN: 0006-3495
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- Citations: 77
Verbridge SS, Edel JB, Stavis SM, et al., 2005, Suspended glass nanochannels coupled with microstructures for single molecule detection, JOURNAL OF APPLIED PHYSICS, Vol: 97, ISSN: 0021-8979
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- Citations: 44
Edel JB, Wu M, Baird B, et al., 2005, High spatial resolution observation of single-molecule dynamics in living cell membranes, BIOPHYSICAL JOURNAL, Vol: 88, Pages: L43-L45, ISSN: 0006-3495
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- Citations: 47
Stavis SM, Edel JB, Li Y, et al., 2005, Spectral and mobility measurements of single fluorescent nanobarcodes in submicrometer fluidic channels, Pages: 718-720
Fluorescent nanobarcodes have been developed by nucleic acid engineers to specifically and uniquely label biomolecules. Submicrometer fluidic channels were used to detect and identify individual nanobarcodes by their fluorescence emission and mobility. Two optical configurations were used. Focused 488 nm and 568 nm lasers were either overlapped or separated along the channel length to measure the spectral profile and speed of single nanobarcodes. Nanobarcodes were individually identifiable with varying degrees of accuracy. Copyright © 2005 by the Transducer Research Foundation, Inc.
Stavis SM, Edel JB, Samiee KT, et al., 2005, Single molecule studies of quantum dot conjugates in a submicrometer fluidic channel, 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 USA, 49th Annual Meeting of the Biopysical-Society, Publisher: Biophysical Society, Pages: 163A-164A, ISSN: 0006-3495
Edel JB, Wu M, Baird B, et al., 2005, High spatial resolution observation of single molecule dynamics in living cell membranes using zero mode waveguides, 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 USA, 49th Annual Meeting of the Biopysical-Society, Publisher: BIOPHYSICAL SOCIETY, Pages: 195A-195A, ISSN: 0006-3495
Verbridge S, Edel JB, Stavis SM, et al., 2005, Nanofluidics meets single molecule spectroscopy: an approach to single fluorophore resolution, USA, 2005 American Physical Society March Meeting, Publisher: APS
Stavis SM, Edel JB, Samiee KT, et al., 2005, Single molecule studies of quantum dot conjugates in a submicrometer fluidic channel, LAB ON A CHIP, Vol: 5, Pages: 337-343, ISSN: 1473-0197
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- Citations: 82
Beard NP, Edel JB, deMello AJ, 2004, Integrated on-chip derivatization and electrophoresis for the rapid analysis of biogenic amines, ELECTROPHORESIS, Vol: 25, Pages: 2363-2373, ISSN: 0173-0835
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- Citations: 51
Leung SA, Edel JB, Wootton RCR, et al., 2004, Continuous real-time bubble monitoring in microchannels using refractive index detection, MEASUREMENT SCIENCE AND TECHNOLOGY, Vol: 15, Pages: 290-296, ISSN: 0957-0233
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- Citations: 15
de Mello AJ, Edel JB, Hill EK, 2004, Detection of single molecules in liquids, Encyclopedia of modern optics, Editors: Guenther, Steel, Guenther, Steel, Publisher: Academic Press, Pages: 21-30, ISBN: 9780122276002
Edel JB, Beard NP, Hofmann O, et al., 2004, Thin-film polymer light emitting diodes as integrated excitation sources for microscale capillary electrophoresis, LAB ON A CHIP, Vol: 4, Pages: 136-140, ISSN: 1473-0197
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- Citations: 67
Edel JB, de Mello AJ, 2003, Determination of single particle flow velocities in microchannels using a maximum likelihood estimator method, PHYSICAL CHEMISTRY CHEMICAL PHYSICS, Vol: 5, Pages: 3973-3978, ISSN: 1463-9076
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- Citations: 6
Edel JB, de Mello AJ, 2003, Single particle confocal fluorescence spectroscopy in microchannels: Dependence of burst width and burst area distributions on particle size and flow rate, ANALYTICAL SCIENCES, Vol: 19, Pages: 1065-1069, ISSN: 0910-6340
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- Citations: 9
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