Publications
11 results found
Ross JR, Riley J, 2008, Commentary: Controversies in SIGN guidance on pain control in patients with cancer, BRITISH MEDICAL JOURNAL, Vol: 337, ISSN: 0959-535X
- Author Web Link
- Cite
- Citations: 1
Droney M, Gretton SK, Ross JR, et al., 2008, OPIOID RECEPTORS AND ANALGESIC RESPONSE TO MORPHINE IN CANCER PATIENTS, 33rd European-Society-for-Medical-Oncology Congress, Publisher: OXFORD UNIV PRESS, Pages: 273-273, ISSN: 0923-7534
Droney J, Ross J, Gretton S, et al., 2008, Constipation in cancer patients on opioids, Supportive Care in Cancer, Vol: 16, Pages: 453-459
Ross JR, Riley J, Taegetmeyer A, et al., 2008, Genetic variation and response to morphine in cancer patients: Catechol-O-Methyltransferase (COMT) and multi-drug resistance (MDR-1) gene polymorphisms are associated with central side-effects., Cancer, Vol: 112, Pages: 1390-1403
Riley J, Ross JR, Gretton SK, et al., 2007, Proposed 5-step World Health Organization analgesic and side effect ladder, 3rd Asia Pacific Symposium on Pain Control, Publisher: WILEY, Pages: 23-30, ISSN: 1090-3801
- Author Web Link
- Cite
- Citations: 7
Ross JR, Riley J, Quigley C, et al., 2006, Clinical pharmacology and pharmacotherapy of opioid switching in cancer patients, ONCOLOGIST, Vol: 11, Pages: 765-773, ISSN: 1083-7159
- Author Web Link
- Cite
- Citations: 28
Riley J, Ross JR, Rutter D, et al., 2006, No pain relief from morphine? Individual variation in sensitivity to morphine and the need to switch to an alternative opioid in cancer patients, SUPPORTIVE CARE IN CANCER, Vol: 14, Pages: 56-64, ISSN: 0941-4355
- Author Web Link
- Cite
- Citations: 95
Ross JR, Goller K, Hardy J, et al., 2005, Gabapentin is effective in the treatment of cancer-related neuropathic pain: a prospective, open-label study., J Palliat Med, Vol: 8, Pages: 1118-1126, ISSN: 1096-6218
BACKGROUND: Gabapentin has been evaluated in the treatment of nonmalignant neuropathic pain, however, there is little direct evidence evaluating its efficacy in cancer-related neuropathic pain. OBJECTIVE: This study evaluated the effectiveness of gabapentin to treat cancer-related neuropathic pain. DESIGN: This was an open-label study. Two parallel groups of patients were recruited with either treatment-related (radiotherapy, surgery, chemotherapy) or tumor-related neuropathic pain. Gabapentin was dose-escalated from 300 mg/d to 1.8 g/d. MEASUREMENTS: The primary outcome, pain, was assessed using the modified brief pain inventory. In addition patient descriptors of pain and scores of activities of daily living were collated together with demographic data. RESULTS: We recruited 62 patients with treatment-related (n = 25) or tumor-related (n = 37) neuropathic pain. There was a significant reduction in the worst, average, and current pain scores (p < 0.002), but not the least pain score (p = 0.21). Twenty-eight of 62 (45.2%) of patients achieved at least a one third reduction in pain score (95% confidence interval [CI] 32.5-58.3); the number needed to treat to obtain this benefit is 2.2 (95% CI 1.7-3.1). There was a significant reduction in all scores measuring the impact of pain on daily living (p < 0.003). There was no significant difference in pain scores at day 8 compared to day 15. Analysis of variance suggested that gender, but not etiology, or type of neuropathic pain, was a significant predictor of analgesic response and this warrants further investigation. CONCLUSION: We conclude that gabapentin is an effective treatment for cancer-related neuropathic pain.
Ross JR, Rutter D, Welsh K, et al., 2005, Clinical response to morphine in cancer patients and genetic variation in candidate genes, PHARMACOGENOMICS JOURNAL, Vol: 5, Pages: 324-336, ISSN: 1470-269X
- Author Web Link
- Cite
- Citations: 106
Riley J, Ross JR, Rutter D, et al., 2004, A retrospective study of the association between haematological and biochemical parameters and morphine intolerance in patients with cancer pain, PALLIATIVE MEDICINE, Vol: 18, Pages: 19-24, ISSN: 0269-2163
- Author Web Link
- Cite
- Citations: 21
KHOO D, HALL E, MOTSON R, et al., 1994, PALLIATION OF MALIGNANT INTESTINAL-OBSTRUCTION USING OCTREOTIDE, EUROPEAN JOURNAL OF CANCER, Vol: 30A, Pages: 28-30, ISSN: 0959-8049
- Author Web Link
- Cite
- Citations: 64
This data is extracted from the Web of Science and reproduced under a licence from Thomson Reuters. You may not copy or re-distribute this data in whole or in part without the written consent of the Science business of Thomson Reuters.