Publications
285 results found
Sepulveda P, Jones JR, Hench LL, 2002, Synthesis of sol-gel derived bioactive foams, Zurich-Uetikon, 14th international symposium on ceramics in medicine (BIOCERAMICS-14), Palm Springs, California, 14 - 17 November 2001, Publisher: Trans Tech Publications, Pages: 287-290
Jones JR, Sepulveda P, Hench LL, 2002, Concentration dependence of bioactive glass dissolution in vitro, Zurich-Uetikon, 14th international symposium on ceramics in medicine (BIOCERAMICS-14), Palm Springs, California, 14 - 17 November 2001, Publisher: Trans Tech Publications, Pages: 303-306
Manson-Whitton ED, Stone IC, Jones JR, et al., 2002, Isothermal grain coarsening of spray formed alloys in the semi-solid state, Acta Materialia, Vol: 50, Pages: 2517-2535, ISSN: 1359-6454
Hench LL, Jones JR, Sepulveda P, 2002, Bioactive materials for tissue engineering scaffolds, Future Strategies for Tissue and Organ Replacement, Editors: Polak, Hench, Kemp, Polak, Hench, Kemp, London, Publisher: Imperial College Press, Pages: 3-24, ISBN: 9781860943119
Notingher I, Boccaccini AR, Jones J, et al., 2002, Application of Raman micro-spectroscopy to the characterisation of biomaterials, Bucharest, Romania, 3rd European conference on advanced materials and technologies
Jones JR, Sepulveda P, Hench LL, 2002, The effect of temperature on the processing and properties of macroporous bioactive glass foams, Zurich-Uetikon, 14th international symposium on ceramics in medicine (BIOCERAMICS-14), Palm Springs, California, 14 - 17 November 2001, Publisher: Trans Tech Publications, Pages: 299-302
Sepulveda P, Jones JR, Hench LL, 2001, Characterization of melt-derived 45S5 and sol-gel-derived 58S bioactive glasses, JOURNAL OF BIOMEDICAL MATERIALS RESEARCH, Vol: 58, Pages: 734-740, ISSN: 0021-9304
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- Citations: 294
Jones JR, Sepulveda P, Hench LL, 2001, Dose-dependent behavior of bioactive glass dissolution, JOURNAL OF BIOMEDICAL MATERIALS RESEARCH, Vol: 58, Pages: 720-726, ISSN: 0021-9304
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- Citations: 183
Jones JR, Hench LL, 2001, Materials perspective - Biomedical materials for new millennium: perspective on the future, MATERIALS SCIENCE AND TECHNOLOGY, Vol: 17, Pages: 891-900, ISSN: 0267-0836
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- Citations: 75
Jones JR, Hench LL, 2001, Biomedical materials for new millennium: Perspective on the future, Materials Science and Technology, Vol: 17, Pages: 891-900, ISSN: 0267-0836
Millions of orthopaedic prostheses made of bioinert materials have been implanted with an excellent 15 year survivability of 75-85%. Improved metal alloys, special polymers, and medical grade ceramics are the basis for this success, which has enhanced the quality of life for millions of patients. However, an increasing percentage of our aging population require greater than 30 years survivability of the devices. It is proposed that to satisfy this growing need for very long term orthopaedic repair a paradigm shift is needed; a shift in emphasis from the replacement of tissues to the regeneration of tissues. Such a shift from a materials and mechanics approach to tissue repair requires an increase in the understanding and utilisation of biologically approaches. Two new biologically orientated alternatives in biomaterials for orthopaedics in the new millennium are discussed: tissue regeneration, where in situ repair is initiated in the host tissue, and tissue engineering, where repair is initiated in vitro on cellularly seeded scaffolds and then transplanted to the recipient. The concept of the use of class A bioactive materials to stimulate the regeneration of trabecular bone is described along with clinical applications. Eleven reaction stages lead to the enhanced proliferation and differentiation of osteoblasts and the recreation of trabecular bone architecture. Recent results showing the effects of microchemical gradients on the genetic activation of bone cells are related to the molecular design of hierarchical bioactive resorbable scaffolds for the tissue engineering of bone constructs.
Sepulveda P, Jones JR, Hench LL, 2001, Effect of particle size on ioglass (R) dissolution, Ceramic materials in orthopaedic surgery: clinical results in the year 2000, Publisher: Trans Tech Publications, Pages: 629-634, ISSN: 1013-9826
Collard DM, Allen SD, Cherrier MC, et al., 1999, New functional copolyesters., Publisher: AMER CHEMICAL SOC, Pages: U632-U632, ISSN: 0065-7727
Collard DM, Jones JR, Liotta CL, et al., 1999, Photocrosslinking of poly(ethylene terephthalate-co-2,6-anthracenedi-carboxylate)., Publisher: AMER CHEMICAL SOC, Pages: U615-U615, ISSN: 0065-7727
Vargas M, Jones JR, Collard DM, et al., 1999, Diels-Alder reactions of poly(ethylene terephthalate-CO-2,6-anthracene dicarboxylate) with maleimides., Publisher: AMER CHEMICAL SOC, Pages: U615-U615, ISSN: 0065-7727
Nommeots-Nomm A, Jones JR, Lee PD, et al., Four-dimensional viscous flow sintering of 3D-printed bioactive glass scaffolds, AMERICAN CERAMIC SOCIETY BULLETIN, Vol: 98, Pages: 38-39, ISSN: 0002-7812
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