Publications
309 results found
Kitchen PA, Fitzgerald AJ, Goodlad RA, et al., 2000, Glucagon-like peptide-2 increases sucrase-isomaltase but not caudal-related homeobox protein-2 gene expression, AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, Vol: 278, Pages: G425-G428, ISSN: 0193-1857
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- Citations: 31
Shaw-Smith CJ, Coffey AJ, Leversha M, et al., 2000, Characterisation of a novel murine intestinal serine protease, DISP, BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION, Vol: 1490, Pages: 131-136, ISSN: 0167-4781
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- Citations: 9
Kitchen RA, Fitzgerald AJ, Goodlad RA, et al., 2000, Glucagon-like peptide-2 increases sucrase-isomaltase but not caudal- related homeobox protein-2 gene expression, American Journal of Physiology - Gastrointestinal and Liver Physiology, Vol: 278, ISSN: 0193-1857
To determine the effect of glucagon-like peptide-2 (GLP-2) on sucrase- isomaltase and caudal-related homeobox protein-2 (Cdx-2) gene expression, male Wistar rats were divided into total parenteral nutrition (TPN)-fed and GLP-2-treated, TPN-fed groups. TPN was given via a jugular line, inserted under anesthesia, for 7 days. The treatment group received 40 μg/day of GLP- 2 intravenously with the TPN diet. The small intestine and colon were weighed and measured. Tissue was obtained from the jejunum, terminal ileum, and midcolon. RNA analysis, morphometry, and microdissection were performed. The weight of the small intestine of GLP-2-treated rats was greater than that of TPN-fed rats (P < 0.001). GLP-2 increased the mean metaphase arrests/crypt in both the jejunum and ileum (P < 0.001). Ileal expression of sucrase- isomaltase was increased by 1.6-fold (P < 0.05). Jejunal expression was increased by a similar amount, although not significantly (P= 0.08). There was no change in Cdx-2 gene expression. Thus G LP-2 can maintain small intestinal morphology and function, but effects on gene expression are not mediated by gross changes in the level of the mRNA for the homeobox protein Cdx-2.
Lindsay JO, Taylor Robinson SD, Jackson JE, et al., 2000, Erratum: The investigation of iron deficiency anemia - A hospital based audit (Hepato-Gastroenterology (1999) 46 (2887-2890)), Hepato-Gastroenterology, Vol: 47, ISSN: 0172-6390
Lindsay JO, Robinson SDT, Jackson JE, et al., 1999, The investigation of iron deficiency anemia - A hospital based audit, HEPATO-GASTROENTEROLOGY, Vol: 46, Pages: 2887-2890, ISSN: 0172-6390
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- Citations: 15
Hodgson RS, Jackson JE, Taylor-Robinson SD, et al., 1999, Superior mesenteric vein stenosis complicating Crohn's disease, GUT, Vol: 45, Pages: 459-462, ISSN: 0017-5749
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- Citations: 5
Barley NF, Prathalingam SR, Zhi P, et al., 1999, Factors involved in the duodenal expression of the human calbindin-D9k gene, BIOCHEMICAL JOURNAL, Vol: 341, Pages: 491-500, ISSN: 0264-6021
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- Citations: 46
Shaw-Smith CJ, Coffey AJ, Huckle E, et al., 1999, Differentially expressed genes in mouse small intestine identified by selective amplification of 3′ end class IIS restriction fragments of cDNA (cDNA indexing)., GASTROENTEROLOGY, Vol: 116, Pages: A578-A578, ISSN: 0016-5085
Shaw-Smith CJ, Coffey AJ, Huckle E, et al., 1999, Identification of a novel distal intestine specific serine protease by cDNA indexing, Publisher: W B SAUNDERS CO-ELSEVIER INC, Pages: A578-A578, ISSN: 0016-5085
Shaw-Smith CJ, Coffey AJ, Huckle E, et al., 1999, A new serine protease expressed in distal intestine identified by cDNA indexing., GUT, Vol: 44, Pages: A87-A87, ISSN: 0017-5749
Walters JRF, Barley NF, Poulsom R, et al., 1999, Human intestinal calbindin-D9k: Transcriptional control of cellular gene expression and vitamin D dependence, Publisher: W B SAUNDERS CO-ELSEVIER INC, Pages: A943-A943, ISSN: 0016-5085
Walters JRF, Barley NF, Poulsom R, et al., 1999, Calbindin-D9k gene expression in human intestine: Studies of transcriptional control, GUT, Vol: 44, Pages: A88-A88, ISSN: 0017-5749
Walters JRF, Howard A, Lowery LJ, et al., 1999, Expression of genes involved in calcium absorption in human duodenum, EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, Vol: 29, Pages: 214-219, ISSN: 0014-2972
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- Citations: 34
Krupicková S, Tucková L, Flegelová Z, et al., 1999, Identification of common epitopes on gliadin, enterocytes, and calreticulin recognised by antigliadin antibodies of patients with coeliac disease, GUT, Vol: 44, Pages: 168-173, ISSN: 0017-5749
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- Citations: 36
Prathalingam SR, Howard A, Barley NF, et al., 1998, Inhibition of luciferase expression from a commercial reporter vector by 1,25-dihydroxycholecalciferol, ANALYTICAL BIOCHEMISTRY, Vol: 263, Pages: 113-115, ISSN: 0003-2697
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- Citations: 4
Howard A, Barley N, Jordinson M, et al., 1998, Reduced expression of the intestinal transcription factors CDX2 and C/EBPα in rats fed by total parenteral nutrition., GASTROENTEROLOGY, Vol: 114, Pages: A883-A883, ISSN: 0016-5085
Barley N, Howard A, Legon S, et al., 1998, Interactions of transcription factors with the promoter of human calbindin-D9k., Publisher: W B SAUNDERS CO, Pages: A350-A350, ISSN: 0016-5085
Tuckova L, Karska K, Walters JRF, et al., 1997, Anti-gliadin antibodies in patients with celiac disease cross-react with enterocytes and human calreticulin, CLINICAL IMMUNOLOGY AND IMMUNOPATHOLOGY, Vol: 85, Pages: 289-296, ISSN: 0090-1229
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- Citations: 37
ShawSmith CJ, Coffey AJ, Campbell EA, et al., 1997, Novel genes identified by selective amplification of 3' end class IIS restriction fragments from mouse ileal cDNA, Publisher: BRITISH MED JOURNAL PUBL GROUP, Pages: A33-A33, ISSN: 0017-5749
Chakravarty P, Howard A, ShawSmith CJ, et al., 1997, The human ileal bile acid binding protein gene promoter, GUT, Vol: 41, Pages: A33-A33, ISSN: 0017-5749
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- Citations: 1
Lindsay JO, TaylorRobinson SD, Walters JRF, 1997, Investigation of iron deficiency anaemia - A role for angiography, Publisher: BRITISH MED JOURNAL PUBL GROUP, Pages: A88-A88, ISSN: 0017-5749
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- Citations: 1
Hodgson RS, TaylorRobinson SD, Jackson JE, et al., 1997, Superior mesenteric vein stenosis complicating Crohn's disease, GUT, Vol: 41, Pages: A222-A222, ISSN: 0017-5749
Walters JRF, Howard A, Rumble HEE, et al., 1997, Differences in expression of homeobox transcription factors in proximal and distal human small intestine, GASTROENTEROLOGY, Vol: 113, Pages: 472-477, ISSN: 0016-5085
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- Citations: 49
Sitrin MD, Bolt MJG, Raman L, et al., 1997, Effect of aging on intestinal calcium transport gene expression in the rat., Publisher: AMER SOC CLINICAL NUTRITION, Pages: 31-31, ISSN: 0002-9165
Sitrin MD, Bolt MJG, Raman L, et al., 1997, Expression of calcium transport genes in a rat model of the short bowel syndrome., Publisher: W B SAUNDERS CO-ELSEVIER INC, Pages: A907-A907, ISSN: 0016-5085
Barley NF, Chakravarty P, Sitrin MD, et al., 1997, Gene expression in transposed segments of rat small intestine., GASTROENTEROLOGY, Vol: 112, Pages: A860-A860, ISSN: 0016-5085
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- Citations: 1
Weir A, TaylorRobinson SD, Poole S, et al., 1997, Cytoplasmic antineutrophil cytoplasmic antibody-positive vasculitis associated with ulcerative colitis, AMERICAN JOURNAL OF GASTROENTEROLOGY, Vol: 92, Pages: 506-508, ISSN: 0002-9270
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- Citations: 10
ShawSmith CJ, Walters JRF, 1997, Regional expression of intestinal genes for nutrient absorption, GUT, Vol: 40, Pages: 5-8, ISSN: 0017-5749
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- Citations: 17
Moss SF, Attia L, Scholes JV, et al., 1996, Increased small intestinal apoptosis in coeliac disease, GUT, Vol: 39, Pages: 811-817, ISSN: 0017-5749
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- Citations: 142
Lambiase P, Seery JP, TaylorRobinson SD, et al., 1996, Resolution of panniculitis after placement of pancreatic duct stent in chronic pancreatitis, AMERICAN JOURNAL OF GASTROENTEROLOGY, Vol: 91, Pages: 1835-1837, ISSN: 0002-9270
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- Citations: 23
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