Justin Mason is Professor of Vascular Rheumatology within Vascular Sciences, National Heart and Lung Institute at Hammersmith Hospital.
Professor Mason leads a basic science research group investigating molecular mechanisms involved in the regulation of vascular endothelial cytoprotection. A more detailed understanding of these mechanisms will facilitate the rational design of novel therapies by which vascular endothelium can be conditioned in order to minimise vascular injury, EC dysfunction and subsequent atherogenesis in patients with systemic inflammatory disease. In addition, he is actively involved in clinical research, which aims to optimise clinical assessment and treatment of the large vessel vasculitides and understand the relationship between chronic endothelial dysfunction and accelerated atherosclerosis. Read more on Justin's research.
Justin graduated in Medicine in 1986 from the University of London and trained in Rheumatology at the Kennedy Institute of Rheumatology, Charing Cross Hospital and at the Royal Postgraduate Medical School in London. Following award of a Medical Research Council Training Fellowship in 1992 and subsequently a PhD degree in 1996 from Imperial College London, he was awarded an Arthritis Research Campaign Senior Research Fellowship in 2000. He is a Fellow of the Royal College of Physicians in London and of the Association of Physicians of Great Britain and Ireland, and is the Chair of the Arthritis Research UK - Research Education and Capacity Committee, a member of the Medical Research Society Committee and the British Heart Foundation Project Grant Committee..
et al., 2018, Giant cell arteritis: new concepts, treatments and the unmet need that remains., Rheumatology (oxford)
et al., 2018, Novel Angiographic Scores for evaluation of Large Vessel Vasculitis, Scientific Reports, Vol:8, ISSN:2045-2322
Pearson JD, Mason JC, 2018, Reactive oxygen species as drivers of autoimmune pathology: an Introduction to Special Issue "Oxidative stress and altered redox signalling in autoimmune and connective tissue diseases", Free Radical Biology and Medicine, Vol:125, ISSN:0891-5849, Pages:1-2
et al., 2018, Celecoxib exerts protective effects in the vascular endothelium via COX-2-independent activation of AMPK-CREB-Nrf2 signalling, Scientific Reports, Vol:8, ISSN:2045-2322
Tombetti E, Mason JC, 2018, Takayasu arteritis: advanced understanding is leading to new horizons., Rheumatology (oxford)