Publications
58 results found
Brown KA, 2010, A brief perspective of the determination of crystal structures of site-directed mutants of tyrosyl-tRNA synthetase, PROTEIN ENGINEERING DESIGN & SELECTION, Vol: 24, Pages: 229-231, ISSN: 1741-0126
Albesa-Jove D, Bertrand T, Carpenter EP, et al., 2010, Four Distinct Structural Domains in <i>Clostridium difficile</i> Toxin B Visualized Using SAXS, JOURNAL OF MOLECULAR BIOLOGY, Vol: 396, Pages: 1260-1270, ISSN: 0022-2836
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- Citations: 45
Hill J, Leary S, Smither S, et al., 2009, N255 is a key residue for recognition by a monoclonal antibody which protects against <i>Yersinia pestis</i> infection, VACCINE, Vol: 27, Pages: 7073-7079, ISSN: 0264-410X
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- Citations: 18
Tanabe M, Szakonyi G, Brown KA, et al., 2009, The multidrug resistance efflux complex, EmrAB from <i>Escherichia coli</i> forms a dimer <i>in vitro</i>, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Vol: 380, Pages: 338-342, ISSN: 0006-291X
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- Citations: 47
Fagan RP, Albesa-Jove D, Qazi O, et al., 2009, Structural insights into the molecular organization of the S-layer from <i>Clostridium difficile</i>, MOLECULAR MICROBIOLOGY, Vol: 71, Pages: 1308-1322, ISSN: 0950-382X
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- Citations: 100
Metcalfe C, Macdonald IK, Murphy EJ, et al., 2008, The tuberculosis prodrug isoniazid bound to activating peroxidases, JOURNAL OF BIOLOGICAL CHEMISTRY, Vol: 283, Pages: 6193-6200, ISSN: 0021-9258
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- Citations: 67
Bowyer PW, Tate EW, Leatherbarrow RJ, et al., 2008, <i>N</i>-myristoyltransferase:: a prospective drug target for protozoan parasites, CHEMMEDCHEM, Vol: 3, Pages: 402-408, ISSN: 1860-7179
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- Citations: 54
Bowyer PW, Gunaratne RS, Grainger M, et al., 2007, Molecules incorporating a benzothiazole core scaffold inhibit the N-myristoyltransferase of <i>Plasmodium falciparum</i>, BIOCHEMICAL JOURNAL, Vol: 408, Pages: 173-180, ISSN: 0264-6021
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- Citations: 55
Tanabe M, Mirza O, Bertrand T, et al., 2007, Structures of OppA and PstS from <i>Yersinia pestis</i> indicate variability of interactions with transmembrane domains, ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY, Vol: 63, Pages: 1185-1193, ISSN: 2059-7983
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- Citations: 21
Harland DN, Chu K, Haque A, et al., 2007, Identification of a LolC homologue in <i>Burkholderia pseudomallei</i>, a novel protective antigen for melioidosis, INFECTION AND IMMUNITY, Vol: 75, Pages: 4173-4180, ISSN: 0019-9567
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- Citations: 50
Vaithanomsat P, Brown KA, 2007, Isolation and mutation of recombinant EPSP synthase from pathogenic bacteria <i>Pseudomonas aeruginosa</i>, PROCESS BIOCHEMISTRY, Vol: 42, Pages: 592-598, ISSN: 1359-5113
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- Citations: 11
Harding SV, Sarkar-Tyson M, Smither SJ, et al., 2007, The identification of surface proteins of <i>Burkholderia pseudomallei</i>, VACCINE, Vol: 25, Pages: 2664-2672, ISSN: 0264-410X
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- Citations: 41
Harland DN, Dassa E, Titball RW, et al., 2007, ATP-binding cassette systems in <i>Burkholderia pseudomallei</i> and <i>Burkholderia mallei</i>, BMC GENOMICS, Vol: 8, ISSN: 1471-2164
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- Citations: 30
Qazi O, Bolgiano B, Crane D, et al., 2007, The H<sub>C</sub> fragment of tetanus toxin forms stable, concentration-dependent dimers <i>via</i> an intermolecular disulphide bond, JOURNAL OF MOLECULAR BIOLOGY, Vol: 365, Pages: 123-134, ISSN: 0022-2836
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- Citations: 13
Panethymitaki C, Bowyer PW, Price HP, et al., 2006, Characterization and selective inhibition of myristoyl-CoA:protein <i>N</i>-myristoyltransferase from <i>Trypanosoma brucei</i> and <i>Leishmania major</i>, BIOCHEMICAL JOURNAL, Vol: 396, Pages: 277-285, ISSN: 0264-6021
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- Citations: 51
Tanabe M, Atkins HS, Harland DN, et al., 2006, The ABC transporter protein OppA provides protection against experimental <i>Yersinia pestis</i> infection, INFECTION AND IMMUNITY, Vol: 74, Pages: 3687-3691, ISSN: 0019-9567
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- Citations: 57
Tiber PM, Nacar C, Orun O, et al., 2005, Attempts for proper folding of recombinant Goalpha protein after inclusion body purification, 30th Congress of the Federation-of-European-Biochemical-Societies (FEBS)/9th IUBMB Conference, Publisher: WILEY, Pages: 376-376, ISSN: 1742-464X
Keith KE, Oyston PC, Crossett B, et al., 2005, Functional characterization of OXA-57, a class D β-lactamase from <i>Burkholderia pseudomallei</i>, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, Vol: 49, Pages: 1639-1641, ISSN: 0066-4804
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- Citations: 19
Harland DN, Garmory HS, Brown KA, et al., 2005, An association between ATP binding cassette systems, genome sizes and lifestyles of bacteria, RESEARCH IN MICROBIOLOGY, Vol: 156, Pages: 434-442, ISSN: 0923-2508
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- Citations: 15
Eady NAJ, Jesmin NAJ, Servos S, et al., 2005, Probing the function of <i>Mycobacterium tuberculosis</i> catalase-peroxidase by site-directed mutagenesis, DALTON TRANSACTIONS, Pages: 3495-3500, ISSN: 1477-9226
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- Citations: 4
Holden MTG, Titball RW, Peacock SJ, et al., 2004, Genomic plasticity of the causative agent of melioidosis, Burkholderia pseudomallei, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 101, Pages: 14240-14245, ISSN: 0027-8424
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- Citations: 577
Pierattelli R, Banci L, Eady NAJ, et al., 2004, Enzyme-catalyzed mechanism of isoniazid activation in class I and class III peroxidases, JOURNAL OF BIOLOGICAL CHEMISTRY, Vol: 279, Pages: 39000-39009
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- Citations: 50
Bertrand T, Eady NAJ, Jones JN, et al., 2004, Crystal structure of <i>Mycobacterium tuberculosis</i> catalase-peroxidase, JOURNAL OF BIOLOGICAL CHEMISTRY, Vol: 279, Pages: 38991-38999
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- Citations: 162
Park A, Lamb HK, Nichols C, et al., 2004, Biophysical and kinetic analysis of wild-type and site-directed mutants of the isolated and native dehydroquinate synthase domain of the AROM protein, PROTEIN SCIENCE, Vol: 13, Pages: 2108-2119, ISSN: 0961-8368
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- Citations: 10
Sharp KH, Moody PCE, Brown KA, et al., 2004, Crystal structure of the ascorbate peroxidase-salicylhydroxamic acid complex, BIOCHEMISTRY, Vol: 43, Pages: 8644-8651, ISSN: 0006-2960
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- Citations: 55
Garmory HS, Freeman D, Brown KA, et al., 2004, Protection against plague afforded by immunisation with DNA vaccines optimised for expression of the <i>Yersinia pestis</i> V antigen, VACCINE, Vol: 22, Pages: 947-957, ISSN: 0264-410X
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- Citations: 34
Garmory HS, Leary SEC, Griffin KF, et al., 2004, The use of live attenuated bacteria as a delivery system for heterologous antigens, JOURNAL OF DRUG TARGETING, Vol: 11, Pages: 471-479, ISSN: 1061-186X
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- Citations: 45
Garmory HS, Griffin KF, Brown KA, et al., 2003, Oral immunisation with live <i>aroA</i> attenuated <i>Salmonella enterica</i> serovar Typhimurium expressing the <i>Yersinia pestis</i> V antigen protects mice against plague, VACCINE, Vol: 21, Pages: 3051-3057, ISSN: 0264-410X
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- Citations: 48
Brown KA, Carpenter EP, Watson KA, et al., 2003, Twists and turns: a tale of two shikimate-pathway enzymes, BIOCHEMICAL SOCIETY TRANSACTIONS, Vol: 31, Pages: 543-547, ISSN: 0300-5127
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- Citations: 14
Garmory HS, Titball RW, Brown KA, et al., 2003, Construction and evaluation of a eukaryotic expression plasmid for stable delivery using attenuated <i>Salmonella</i>, MICROBIAL PATHOGENESIS, Vol: 34, Pages: 115-119, ISSN: 0882-4010
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- Citations: 12
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