Publications
513 results found
Chockalingam P, Engel R, Schmid M, et al., 2008, Cerebrovascular accidents in adult patients with congenital heart disease, Publisher: OXFORD UNIV PRESS, Pages: 743-744, ISSN: 0195-668X
Dimopoulos K, Diller GP, Petraco R, et al., 2008, Hyponatremia in adults with congenital heart disease: prevalence and relation to outcome, EUROPEAN HEART JOURNAL, Vol: 29, Pages: 744-744, ISSN: 0195-668X
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- Citations: 2
Lok SI, Winkens B, Dimopoulos K, et al., 2008, Recurrence of cerebrovascular events in young adults with a secundum atrial septal defect, Publisher: OXFORD UNIV PRESS, Pages: 823-823, ISSN: 0195-668X
Dimopoulos K, Di Mario C, Barlis P, et al., 2008, Haemodynamic significance of an anomalous right coronary with inter-arterial course assessed with intracoronary pressure measurements during dobutamine challenge, INTERNATIONAL JOURNAL OF CARDIOLOGY, Vol: 126, Pages: E32-E35, ISSN: 0167-5273
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- Citations: 6
Dimopoulos K, Diller G-P, Koltsida E, et al., 2008, Prevalence, predictors, and prognostic value of renal dysfunction in adults with congenital heart disease, CIRCULATION, Vol: 117, Pages: 2320-2328, ISSN: 0009-7322
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- Citations: 267
Uebing A, Babu-Narayan SV, Diller GP, et al., 2008, Response to letter regarding article, "Right Ventricular Mechanics and QRS Duration in Patients With Repaired Tetralogy of Fallot: Implications of Infundibular Disease", CIRCULATION, Vol: 117, Pages: E301-E301, ISSN: 0009-7322
Petraco R, Dimopoulos K, Rubens M, et al., 2008, Bronchial artery embolization for pulmonary arterial hypertension and recurrent hemoptysis?, AMERICAN JOURNAL OF CARDIOLOGY, Vol: 101, Pages: 1064-1065, ISSN: 0002-9149
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- Citations: 9
Barlis P, Kaplan S, Dimopoulos K, et al., 2008, An indeterminate occlusion duration predicts procedural failure in the recanalization of coronary chronic total occlusions, CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS, Vol: 71, Pages: 621-628, ISSN: 1522-1946
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- Citations: 17
Cauranzano P, Angiolillo DJ, Barbagaflo R, et al., 2008, Complete versus incomplete revascularization in patients with multivessel disease undergoing percurtaneous coronary intervention with drug-eluting stents, 57th Annual Scientific Session of the American-College-of-Cardiology, Publisher: ELSEVIER SCIENCE INC, Pages: B35-B36, ISSN: 0735-1097
Tanigawa J, Barlis P, Dimopoulos K, et al., 2008, Optical coherence tomography to assess malapposition in overlapping drug-eluting stents., EuroIntervention, Vol: 3, Pages: 580-583, ISSN: 1774-024X
AIMS: Overlapping drug-eluting stents (DES) are frequently implanted to cover long segments of diseased and injured vessel, or as a bailout technique for edge dissection or incomplete lesion coverage. DES overlap is, nevertheless, associated with strut malapposition and poor intimal coverage, which may increase the risk of stent thrombosis. The aim of this study is to evaluate stent strut apposition in overlapping DES. METHODS AND RESULTS: We assessed strut apposition in 10 overlapped segments (20 DES, 10 patients, 661 struts) immediately after implantation, using optical coherence tomography (OCT). Struts were defined as malapposed when no contact with the intima was detected by OCT, taking into consideration the strut thickness of each stent type. Despite aggressive stent optimisation using balloons with a final balloon/artery ratio of 1.26+/-0.18 at a maximum inflation pressure of 18.0+/-1.9atm, 41.8+/-21.5% of struts were malapposed in the overlapping segment, compared to 20.1+/-17.6% in the proximal and 9.7+/-10.6% in the distal segment (p </=0.05 for both). CONCLUSIONS: OCT revealed that 40% of struts within an overlapped DES segment were malapposed, and this may explain the reported delay in endothelialisation in such segments.
Di Mario C, Dudek D, Piscione F, et al., 2008, Immediate angioplasty versus standard therapy with rescue 3 angioplasty after thrombolysis in the Combined Abciximab REteplase Stent Study in Acute Myocardial Infarction (CARESS-in-AMI): an open, prospective, randomised, multicentre trial, LANCET, Vol: 371, Pages: 559-568, ISSN: 0140-6736
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- Citations: 288
Salukhe TV, Dimopoulos K, Sutton R, et al., 2008, Instantaneous effects of resynchronisation therapy on exercise performance in heart failure patients: the mechanistic role and predictive power of total isovolumic time, HEART, Vol: 94, Pages: 59-64, ISSN: 1355-6037
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- Citations: 10
Kaplan S, Barlis P, Kiris A, et al., 2008, Immediate procedural and long-term clinical outcomes following drug-eluting stent implantation to ostial saphenous vein graft lesions., Acute Card Care, Vol: 10, Pages: 88-92, ISSN: 1748-2941
BACKGROUND: Ostial saphenous vein graft (OSVG) lesions were excluded from all the clinical trials demonstrating significantly lower restenosis rates with drug-eluting stents (DES) compared to bare metal stents (BMS). This study aimed to evaluate the efficacy of DES in OSVG lesions by assessing angiographic and 12-month clinical outcomes. METHODS: 70 consecutive patients (70 OSVG lesions) underwent coronary stent implantation between May 2003 and April 2006: 37 lesions received DES and 33 lesions BMS. Endpoints were all cause and cardiovascular mortality, myocardial infarction (MI), target lesion revascularization (TLR), target vessel revascularization (TVR), examined separately and as a combined end-point (major adverse cardiac events, MACE). RESULTS: Procedural (94.6% for DES and 87.9% for BMS) and angiographic (100% for DES and 100% for BMS) success did not differ between the two groups. The only in-hospital events were non-Q wave MI (DES 8.1% versus BMS 12.1%, P=0.69). At 30-day follow-up, there were no other events. Overall, at 1-year follow-up, the BMS group had a higher TLR (30.3% versus 5.4%, P=0.015), TVR (33.3% versus 10.8%, P=0.045) and MACE rate (36.4% versus 10.8%, P=0.024) compared to the DES group. CONCLUSIONS: Drug-eluting stent implantation to OSVG lesions achieves better clinical results than BMS but is still associated with a relatively high incidence (10.8%) of revascularization at 1-year follow-up.
Dimopoulos K, gatzoulis MA, 2008, Heart failure in Adults with Congenital Heart Disease, Cardiopatie congenite dell'adulto, Editors: Calabro, Sarubbi, Dalla Volta, ISBN: 9788829920082
Dimopoulos K, gatzouilis MA, 2008, Cyanosis in adults with congenital heart disease, Cardiopatie congenite dell'adulto, ISBN: 9788829920082
Barlis P, Kaplan S, Dimopoulos K, et al., 2008, Comparison of bare-metal and sirolimus- or paclitaxel-eluting stents for aorto-ostial coronary disease, CARDIOLOGY, Vol: 111, Pages: 270-276, ISSN: 0008-6312
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- Citations: 17
Diller G-P, Dimopoulos K, Kafka H, et al., 2007, Model of chronic adaptation: right ventricular function in Eisenmenger syndrome, Workshop on Right Ventricular Function and Pulmonary Hypertension, Publisher: OXFORD UNIV PRESS, Pages: H54-H60, ISSN: 1520-765X
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- Citations: 33
Kaplan S, Barlis P, Kiris A, et al., 2007, Immediate procedural and long-term clinical outcomes after drug eluting stent implantation to ostial saphenous vein graft lesions, 19th Annual Transcatheter Cardiovascular Therapeutics Symposium, Publisher: EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC, Pages: 103L-103L, ISSN: 0002-9149
Uebing A, Gibson DG, Babu-Narayan SV, et al., 2007, Right ventricular mechanics and QRS duration in patients with repaired tetralogy of Fallot - Implications of infundibular disease, CIRCULATION, Vol: 116, Pages: 1532-1539, ISSN: 0009-7322
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- Citations: 90
Tanigawa J, Barlis P, Dimopoulos K, et al., 2007, Strut malapposition in overlapping drug-eluting stents by optical coherence tomography, EUROPEAN HEART JOURNAL, Vol: 28, Pages: 200-201, ISSN: 0195-668X
Giannakoulas G, Dimopoutos K, Gatzoulis MA, 2007, Deep vein thrombosis in a patient with congenital heart disease and permanent transfemoral pacing, EUROPACE, Vol: 9, Pages: 851-851, ISSN: 1099-5129
di Mario C, Dimopoulos K, 2007, The effect of drug-eluting stents on collateral coronary flow, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Vol: 50, Pages: 560-560, ISSN: 0735-1097
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- Citations: 1
Kaplan S, Dimopoulos K, La Manna A, et al., 2007, Culotte versus T-stenting in bifurcation lesions: Immediate clinical and angiographic results and midterm clinical follow-up, AMERICAN HEART JOURNAL, Vol: 154, Pages: 336-343, ISSN: 0002-8703
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- Citations: 40
Diller G-P, Dimopoulos K, Kaya MG, et al., 2007, Long-term safety, tolerability and efficacy of bosentan in adults with pulmonary arterial hypertension associated with congenital heart disease, HEART, Vol: 93, Pages: 974-976, ISSN: 1355-6037
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- Citations: 75
Diller G-P, Dimopoulos K, Benson LR, et al., 2007, Ventilatory efficiency and heart rate response are the strongest exercise markers of outcome in non-cyanotic adults with congenital heart disease, 56th Annual Scientific Session of the American-College-of-Cardiology, Publisher: ELSEVIER SCIENCE INC, Pages: 268A-268A, ISSN: 0735-1097
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- Citations: 3
Tanigawa J, Barlis P, Dimopoulos K, et al., 2007, Stent strut apposition of cypher select and Taxus liberte: A prospective optical coherence tomography study, i2 Summit 2007 on Innovation in Intervention, Publisher: ELSEVIER SCIENCE INC, Pages: 35B-35B, ISSN: 0735-1097
Barlis P, Kaplan S, Dimopoulos K, et al., 2007, Culotte versus T-stenting in bifurcation lesions: Immediate clinical and angiographic results and midterm clinical follow-up, i2 Summit 2007 on Innovation in Intervention, Publisher: ELSEVIER SCIENCE INC, Pages: 20B-20B, ISSN: 0735-1097
Muhil IFV, Dimopoulos K, Lawrence RA, et al., 2007, Cachexia as a predictor of mortality among an outpatient population of adults with congenital heart disease, 56th Annual Scientific Session of the American-College-of-Cardiology, Publisher: ELSEVIER SCIENCE INC, Pages: 263A-263A, ISSN: 0735-1097
Goktekin O, Kaplan S, Dimopoulos K, et al., 2007, A new quantitative analysis system for the evaluation of coronary bifurcation lesions: Comparison with current conventional methods, CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS, Vol: 69, Pages: 172-180, ISSN: 1522-1946
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- Citations: 34
Dimopoulos K, Ghilencea L, La Manna A, et al., 2007, Approach to intermediate lesions, Problem Oriented Approaches in Interventional Cardiology, Pages: 123-138, ISBN: 9781841846316
The most frequently used de?nition of an intermediate (IL) or borderline lesion is that of a lesion causing a 40% to 60% diameter stenosis on angiography. This de?nition stems from experimental models showing that a 75% lumen area stenosis corresponding to a 50% lumen diameter stenosis signi?cantly impairs maximal hyperemic ?ow. Nevertheless, visual estimation, which is most often used to evaluate stenosis severity with angiography, is beset by a high inter-observer variability and inaccuracy when compared to physiologic assessment. In one study, only half of the physiologically nonsigni?cant lesions were characterized as such by three independent operators. Presumably for this reason, the most recent American College of Cardiology (ACC) and European Society of Cardiology (ESC) guidelines have broadened the angiographic de?nition of intermediate coronary stenoses up to 70% luminal narrowing (1, 2).
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