Summary
My research focuses on the role of the hypothalamus in the control of energy homeostasis and reproduction. Both of these physiological roles have important implications for human health. I am particularly interested in how the gut senses nutritional status and signals to appetite centres of the brain such as the hypothalamus and brain stem to regulate food intake. I am also interested in how central hypothalamic neuropeptide circuits act to control body weight and reproductive function.
I have won funding from sources including the BBSRC, the MRC, the Technology Strategy Board, the Society for Endocrinology, the British Society for Neuroendocrinology, the British Pharmacological Society and the NC3Rs. I have successfully supervised more than thirty PhD students to completion. I am an honorary fellow of the Royal College of Physicians, Director of Postgraduate Studies (Research) for the Department of Medicine, and Admissions Tutor for the Faculty of Medicine with particular responsibility for widening participation.
Publications
Journals
Watson S, O’Hara H, Reveendran D, et al., 2022, The Power of Suggestion: Subjective Satiety Is Affected by Nutrient and Health-Focused Food Labelling with No Effect on Physiological Gut Hormone Release, Nutrients, Vol:14, Pages:5100-5100
Hope D, Hinds C, Lopes T, et al., 2022, Hypoaminoacidemia Underpins Glucagon-mediated Energy Expenditure and Weight Loss, Cell Reports Medicine, ISSN:2666-3791
Frampton J, Izzi-Engbeaya C, Salem V, et al., 2022, The acute effect of glucagon on components of energy balance and glucose homoeostasis in adults without diabetes: a systematic review and meta-analysis, International Journal of Obesity, Vol:46, ISSN:0307-0565, Pages:1948-1959
Frampton J, Izzi-Engbeaya C, Salem V, et al., 2022, The acute effect of glucagon on components of energy balance and glucose homeostasis in adults without diabetes, International Journal of Obesity, ISSN:0307-0565
Davies DJ, Sam AH, Murphy KG, et al., 2022, BMAT's predictive validity for medical school performance: A retrospective cohort study, Medical Education, Vol:56, ISSN:0308-0110, Pages:936-948