Imperial College London
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ProfessorKatharinaHauck

Faculty of Medicine, School of Public Health

Professor in Health Economics
 
 
 
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Contact

 

+44 (0)20 7594 9197k.hauck Website

 
 
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Assistant

 

Ms Julie Middleton +44 (0)20 7594 3284

 
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Location

 

Office 502School of Public HealthWhite City Campus

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Summary

 

Publications

Citation

BibTex format

@article{Shanaube:2022:10.1371/journal.pone.0278291,
author = {Shanaube, K and Gachie, T and Hoddinott, G and Schaap, A and Floyd, S and Mainga, T and Bond, V and Hayes, R and Fidler, S and Ayles, H and HPTN071, PopART Study Team},
doi = {10.1371/journal.pone.0278291},
journal = {PLoS One},
title = {Depressive symptoms and HIV risk behaviours among adolescents enrolled in the HPTN071 (PopART) trial in Zambia and South Africa},
url = {http://dx.doi.org/10.1371/journal.pone.0278291},
volume = {17},
year = {2022}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - BACKGROUND: Mental health is a critical and neglected public health problem for adolescents in sub-Saharan Africa. In this paper we aim to determine the prevalence of depressive symptoms and the association with HIV risk behaviours in adolescents aged 15-19 years in Zambia and SA. METHODS: We conducted a cross-sectional survey from August-November 2017 in seven control communities of HPTN 071 (PopART) trial (a community-randomised trial of universal HIV testing and treatment), enrolling approximately 1400 eligible adolescents. HIV-status was self-reported. Depressive symptoms were measured with the Short Mood and Feelings Questionnaire (SMFQ), with a positive screen if adolescents scored ≥12. We fitted a logistic regression model to identify correlates of depressive symptoms with subgroup analyses among those who self-reported ever having had sex, by gender and country. RESULTS: Out of 6997 households approached, 6057 (86.6%) were enumerated. 2546 adolescents were enumerated of whom 2120 (83.3%) consented to participate and were administered the SMFQ. The prevalence of depressive symptoms was 584/2120 (27.6%) [95%CI: 25.7%-29.5%]. Adolescents in SA were less likely to experience depressive symptoms (Adjusted Odds Ratio [AOR] = 0.63 (95% CI: 0.50, 0.79), p-value<0.0001). Female adolescents (AOR = 1.46 (95% CI: 1.19, 1.81), p-value<0.0001); those who reported ever having sex and being forced into sex (AOR = 1.80 (95% CI: 1.45, 2.23), p-value<0.001) and AOR = 1.67 (95% CI: 0.99, 2.84); p-value = 0.057 respectively) were more likely to experience depressive symptoms. Among 850 (40.1%) adolescents who self-reported to ever having had sex; those who used alcohol/drugs during their last sexual encounter were more likely to experience depressive symptoms (AOR = 2.18 (95% CI: 1.37, 3.47); p-value = 0.001), whereas those who reported using a condom were less likely to experience depressive symptoms (AOR = 0.74 (95% CI: 0.55, 1.00); p-value = 0.053). CONCLUSION: Th
AU  - Shanaube,K
AU  - Gachie,T
AU  - Hoddinott,G
AU  - Schaap,A
AU  - Floyd,S
AU  - Mainga,T
AU  - Bond,V
AU  - Hayes,R
AU  - Fidler,S
AU  - Ayles,H
AU  - HPTN071,PopART Study Team
DO  - 10.1371/journal.pone.0278291
PY  - 2022///
SN  - 1932-6203
TI  - Depressive symptoms and HIV risk behaviours among adolescents enrolled in the HPTN071 (PopART) trial in Zambia and South Africa
T2  - PLoS One
UR  - http://dx.doi.org/10.1371/journal.pone.0278291
UR  - https://www.ncbi.nlm.nih.gov/pubmed/36454874
UR  - http://hdl.handle.net/10044/1/103667
VL  - 17
ER  -
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