Imperial College London


Central FacultyHuman Resources Division

Consultant, Postdoc Development Centre



+44 (0)20 7594 8873k.hinxman Website




Sherfield BuildingSouth Kensington Campus





Karen is a Consultant within the Postdoc and Fellows Development Centre (PFDC) at Imperial. She gained her PhD in Structural Biology from the University of York, before joining a research institute affiliated with McGill University, Canada. Two years later she returned to the UK to undertake a three year Research Associate position at the University of Warwick. During her time as a researcher she published several publications in her maiden name, Ruane.  

She is passionate about helping early career researchers reach their full potential. Over the last five years she has achieved this by developing a range of tailored training and support for postdocs and fellows from across the College.

Course delivery 

Karen currently delivers the following courses for the PFDC at Imperial: 

Working with Departments 

She works closely with departments through hosting the PFDC Reps Network, a College wide network of Postdocs who are spread across all departments and campuses and total 70 representatives.  She also initiated and coordinates the annual Faculty of Engineering Dame Julia Higgins Postdoc Collaborative Fund and the Fellows and Clinicians Seed Fund.  

To find out more about the activities that Karen and the PFDC team are involved in, please go to the Postdoc and Fellows Development Centre website, or follow us on twitter @ImperialPFDC



Ruane KM, Lloyd AJ, Fülöp V, et al., 2013, Specificity determinants for lysine incorporation in Staphylococcus aureus peptidoglycan as revealed by the structure of a MurE enzyme ternary complex., J Biol Chem, Vol:288, Pages:33439-33448

Majce V, Ruane KM, Gobec S, et al., 2013, Crystallization and preliminary X-ray analysis of a UDP-MurNAc-tripeptide D-alanyl-D-alanine-adding enzyme (PaMurF) from Pseudomonas aeruginosa., Acta Crystallogr Sect F Struct Biol Cryst Commun, Vol:69, Pages:503-505

Rangarajan ES, Ruane KM, Proteau A, et al., 2011, Structural and enzymatic characterization of NanS (YjhS), a 9-O-Acetyl N-acetylneuraminic acid esterase from Escherichia coli O157:H7., Protein Sci, Vol:20, Pages:1208-1219

Quan S, Koldewey P, Tapley T, et al., 2011, Genetic selection designed to stabilize proteins uncovers a chaperone called Spy., Nat Struct Mol Biol, Vol:18, Pages:262-269

Ruane KM, Davies GJ, Martinez-Fleites C, 2008, Crystal structure of a family GT4 glycosyltransferase from Bacillus anthracis ORF BA1558., Proteins, Vol:73, Pages:784-787

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